Vertebral artery aneurysm rupture and hemothorax in a patient with neurofibromatosis Type-1: A case report and review of the literature

Genetic and heritable considerations in patients or families with both intracranial and extracranial aneurysms

“…53 A case report describing a patient with NF1 who had a ruptured vertebral artery aneurysm presented a literature review describing 24 cases of extradural vertebral artery aneurysms, half of which ruptured, in patients with NF1. 57 Another case report described a patient with NF1 who had 8 intracranial aneurysms, and their review found 45 cases of intracranial aneurysms in patients with NF1; 18 of them had multiple aneurysms and 23 patients experienced intracranial hemorrhage as a result. 58 Despite the frequency and morbidity of vascular lesions in patients with NF1, there currently exist no recommended screening guidelines for intra-or extracranial aneurysms or vasculopathies in this population.…”

“…58 Despite the frequency and morbidity of vascular lesions in patients with NF1, there currently exist no recommended screening guidelines for intra-or extracranial aneurysms or vasculopathies in this population. 57…”