Vertebral Fracture in Osteoporosis

Suk, Se Il; Lee, Choon-Ki; Kang, Heung Sik; Lee, Ji Ho; Min, Hak Jin; Hoon, Sang; Chung, Yuong Jin

doi:10.4055/jkoa.1993.28.3.980

Cited by 17 publications

(4 citation statements)

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“…Therefore, BMD examinations are important for preventing fractures and providing interventions to improve BMD. Moreover, appropriate measures based on accurate BMD measurements enable the early prevention and treatment of osteoporosis-related complications 2 ) .…”

Section: Introductionmentioning

confidence: 99%

Comparison of vertebral and femoral bone mineral density in adult females

et al. 2016

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[Purpose] This study assessed vertebral and femoral bone mineral density in adult females. [Subjects and Methods] A total of 314 females in their 40s to 70s were divided into normal, osteopenia, and osteoporosis groups and their vertebral and femoral bone mineral densities were compared. [Results] Comparisons of T scores revealed significant differences among measurements of the third lumbar vertebra, femoral neck, Ward’s triangle, and femoral trochanter. Pearson correlation coefficients were used to assess differences between the vertebral and femoral measurements, and significant differences and positive correlations were observed among third lumbar vertebra, femoral neck, Ward’s triangle, and femur trochanter in the normal group. [Conclusion] Females in the normal, osteopenia, and osteoporosis groups showed significant differences in their third lumbar vertebrae. The lack of significant differences among measurements in the osteoporosis group in this study suggests that patients with osteoporosis require careful and accurate diagnosis.

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Section: Introductionmentioning

confidence: 99%

Comparison of vertebral and femoral bone mineral density in adult females

et al. 2016

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“…Based on previous studies, it has been known that osteoporotic spinal fractures have a relatively good prognosis, and acute pain disappears after 6 to 8 weeks, without causing severe physical or emotional impairment [1,6]. However, recent studies also reported that, once occurred, fracture results in physical and emotional disability in many patients, causing limitations in daily life due to persistent pain, loss of confidence, and depression even after recovery [1,4,19]. Furthermore, the progression of vertebral body compression may cause digestive disorders, such as early satiety and weight loss, due to decreased abdominal cavity volume following costal margin displacement towards the iliac crest, or due to hepatic function deterioration following pleural compression [1][2][3].…”

Section: Discussionmentioning

confidence: 99%

“…Particularly, when accompanied by osteoporosis, spinal compression fractures can result from even a mild trauma or without any noticeable trauma, which is known to occur in 25% of all females over the age of 70 and 50% of all females over the age of 80 [1][2][3]. In the past, osteoporotic spinal compression fractures were thought to recover spontaneously without specific complications; however, with the recent increasing aging population and more osteoporosis-focused studies, these fractures are now reported to have physical, functional, and psychological sequelae, as well as cause serious complications, such as reduced quality of life and increased mortality, suggesting the need for an active therapeutic approach alongside osteoporosis treatment [1,4,5].…”

Section: Introductionmentioning

confidence: 99%

Clinical and radiological outcomes of denosumab and teriparatide treatment in elderly patients with osteoporotic spinal compression fracture without vertebroplasty

Jung

Lee

et al. 2021

J Korean Soc Geriatr Neurosurg

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Vertebroplasty is a common treatment for osteoporotic spinal compression fractures, but it poses complication risk. Therefore, we investigated the clinical and radiological outcomes of conservative treatment using a combination of denosumab and teriparatide. Methods: This study included 86 patients aged 75 or older who were diagnosed with osteoporotic spinal compression fracture from January 2011 to April 2021. The patients were then categorized into those who received denosumab and teriparatide combination treatment without vertebroplasty(group A) and those who received bisphosphonate treatment and underwent vertebroplasty(group B). Several parameters were analyzed: age, sex, underlying diseases, BMI, hospital stay, the time of ambulation start, BMD, VAS score, compression ratio, regional Cobb angle, and local kyphotic angle. Results: As compared to group A, group B showed a relatively shorter hospital stay and time until starting ambulation, but without statistical significance. The VAS scores measured at the time of injury, post-treatment, 3months post-injury, and 1year post-injury did not show statistically significant differences between the groups. In contrast, the mean BMD measured at the time of injury and 1year post-injury demonstrated statistically significant improvements in group A compared to group B. The differences in the compression ratio, regional Cobb angle, and local kyphotic angle measured at the time of injury and 1year post-injury were not statistically significant. Conclusion:Combination treatment without vertebroplasty did not show significant differences in either clinical or radiologic results compared to vertebroplasty cases. Therefore, denosumab and teriparatide combination treatment could be considered as an alternative option for osteoporotic spinal compression fracture patients.

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“…By the age of 75 yrs about 25% of all women have had at least one vertebral compression fractures which increases to 50% at the age of 80 yrs [1,2]. [4][5][6]. hence this study aims to evaluate and analyze the short term functional outcome of Vertebroplasty in the management of stable osteoporotic wedge compression fractures of both lumbar and thoracic vertebrae.…”

Section: Short Research Articlementioning

confidence: 99%

Short Term Follow Up of Patients with Osteoporotic Vertebral Compression Fractures Treated with Percutaneous Vertebroplasty

Balaraman

2021

JPRI

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Vertebral compression fractures are the most common osteoporotic fractures, 30-50% of all women develop vertebral compression fractures. In this study the mean age of 64 years with youngest case of age of 55 years and oldest case. 55 % of patients included in the study are female. One case had systemic hypertension, one case had Parkinsonism, and one case had Coronary Artery Disease. A significant reduction in analgesic intake was revealed. The patients without any analgesics increased from 0.5% (n=2) pre operative to 85.7% (n=30) at the six months follow-up (P less than 0.0001). pain score of ODS for immediate, 1month, 2 month, 3rd month and 6 month and found that(patient active measure) pam is reduced after immediate to 1 month till 6 month(p<0.05), and after 3 rd month to 6 month no difference in pam score was observed.

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Vertebral Fracture in Osteoporosis

Cited by 17 publications

References 0 publications

Comparison of vertebral and femoral bone mineral density in adult females

Comparison of vertebral and femoral bone mineral density in adult females

Clinical and radiological outcomes of denosumab and teriparatide treatment in elderly patients with osteoporotic spinal compression fracture without vertebroplasty

Short Term Follow Up of Patients with Osteoporotic Vertebral Compression Fractures Treated with Percutaneous Vertebroplasty

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