Vertebral fractures and abdominal aortic aneurysm revealing Q fever

Michel, Murielle; Césini, Johann; Michon, J.; Dargère, S.; Vergnaud, M.; Marcelli, Christian

doi:10.1016/j.jbspin.2015.08.001

Cited by 4 publications

(3 citation statements)

References 6 publications

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“…Microbiological investigations revealed the diagnosis of chronic Q fever. 36 Table 2. Summary of positive and negative PET-CT findings in proven chronic Q fever within the retrospective and prospective studies.…”

Section: Pet-ct's Emerging Rolementioning

confidence: 99%

Utility of positron emission tomography imaging in the diagnosis of chronic Q fever: A Systematic Review

et al. 2021

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Chronic Q fever is a diagnostic challenge. Diagnosis relies on serology and/or the detection of DNA from blood or tissue samples. PET-CT identifies tissues with increased glucose metabolism, thus identifying foci of inflammation. Our aim was to review the existing literature on the use of PET-CT to help diagnose chronic Q fever. A literature search was conducted in PubMed and Google Scholar to ascertain publications that included the terms 'Positron Emission Tomography' and 'PET CT' in combination with subheadings 'chronic Q fever' and 'Coxiella burnetii' within the search. To broaden our search retrieval, we used the terms 'chronic Q fever' and 'PET-CT'. Published literature up to 16 th April 2020 was included. 274 articles were initially identified. Post-exclusion criteria, 46 articles were included. Amongst case reports and series, the most frequent focus of infection was vascular, followed by musculoskeletal then cardiac. 79.5% of patients had a focus detected with 55.3% of these having proven infected prosthetic devices. Amongst the retrospective and prospective studies, a total of 394 positive sites of foci were identified with 186 negative cases. Some had follow-up scans (53), with 75.5% showing improvement or resolution. Average timeframe for documented radiological resolution postinitiating treatment was 8.86 months. PET-CT is a useful tool in the management of chronic Q fever. Knowledge of a precise focus enables for directed surgical management helping reduce microbial burden, preventing future complications. Radiological resolution of infection can give clinicians reassurance on whether antimicrobial therapy can be ceased earlier, potentially limiting side effects.

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Section: Pet-ct's Emerging Rolementioning

confidence: 99%

Utility of positron emission tomography imaging in the diagnosis of chronic Q fever: A Systematic Review

et al. 2021

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“…A wide array of clinical presentations with a typical indolent course makes them a diagnostic challenge. [2] A known risk factors for infection are vascular prostheses and aneurysms. [2] These sites have also been shown rarely to spread either by direct contact or through hematogenous routes to the spine.…”

Section: Introductionmentioning

confidence: 99%

“…[2] A known risk factors for infection are vascular prostheses and aneurysms. [2] These sites have also been shown rarely to spread either by direct contact or through hematogenous routes to the spine. [2] We report a patient with the previous vascular surgery and Q fever spinal osteomyelitis.…”

Section: Introductionmentioning

confidence: 99%

Coxiella burnetii infection of the spine requiring neurosurgical intervention

Lundy

Arnold

Hance

2019

Surgical Neurology International

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Background: Infections from Coxiella burnetii, resulting in what is known as Q fever, are relatively rare and difficult to diagnose. Very few reports of spinal infection from C. burnetii have been reported rarely have these cases required surgical intervention. Case Description: We report a patient with the previous vascular surgery and Q fever spinal osteomyelitis. Previously reported cases with spinal involvement have described initial infection of vascular grafts in proximity to the spine. Literature on spinal infection from C. burnetii reports only one case that required surgical intervention of the spine. We report a patient with L5-S1 diskitis who required surgical intervention and subsequent percutaneous drainage. Conclusion: Spinal infections from C. burnetii are rare; however, in the setting of a patient with osteodiscitis with negative cultures as well as a history of significant vascular disease with stents, the diagnosis of Q fever should be entertained. Operative and interventional procedures should also be considered in these patients to help alleviate pain and maintain neurologic function.

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