Vertebral Osteomyelitis Due to Rhodococcus equi in a Liver Transplant Recipient

Fischer, Lutz; Sterneck, Martina; Albrecht, Helmut; Krupski, G.; Polywka, Susanne; Rogiers, Xavier; Broelsch, Christoph E.

doi:10.1086/514596

Cited by 26 publications

(17 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…He was successfully treated with a combination of erythromycin, ciprofloxacin, and rifampicin. A case of vertebral osteomyelitis due to R. equi in a liver transplant recipient 7 mo after transplantation was reported by Fischer et al [42] . The patient was initially diagnosed with a recurrent pneumonia and a pleura-based lung abscess and subsequently developed osteomyelitis of the lower thoracic spine.…”

Section: Rhodococcus Equi Infection In the Liver Transplant Patientmentioning

confidence: 92%

“…Several cases have been described in patients with immunosuppression due to either human immunodeficiency infection, therapy for neoplastic disorders, or kidney and heart transplantation. 15 patients with a R. equi infection following solid-organ transplantation have been described in the literature [42][43][44][45] . In all patients, rhodococcal infection presented late after transplantation (median, 4 years).…”

Section: Rhodococcus Equi Infection In the Liver Transplant Patientmentioning

confidence: 99%

See 1 more Smart Citation

Update and actual trends on bacterial infections following liver transplantation

Pozo

2008

WJG

View full text Add to dashboard Cite

Recent advances in effective antimicrobial prophylactic strategies have led to a decline in the incidence of opportunistic infections in liver transplant recipients. However, morbidity and mortality due to infectious diseases remain as major problems. Bacterial infections occurring early after transplant are mainly related to the technical aspects of the procedure. By contrast, after the first postoperative days and beyond, the nature and variety of infectious complications change. Opportunistic bacterial infections are uncommon after 6 mo in patients receiving stable and reduced maintenance doses of immunosuppression with good graft function and little is documented about these cases in the literature. Transplant recipients may be more susceptible to some pathogens, such as the Nocardia species, Legionella species, Listeria monocytogenes , Mycoplasma species, Salmonella species or Rhodococcus equi. Respiratory infections due to capsulated bacteria, such as Streptococcus pneumoniae and Haemophilus influenza , can be lifethreatening if not promptly treated in this population. These late bacterial infections may be very difficult to recognize and treat in this population. In this article, we review what has been described in the literature with regards to late bacterial infections following liver transplantation.

show abstract

Section: Rhodococcus Equi Infection In the Liver Transplant Patientmentioning

confidence: 92%

Section: Rhodococcus Equi Infection In the Liver Transplant Patientmentioning

confidence: 99%

Update and actual trends on bacterial infections following liver transplantation

Pozo

2008

WJG

View full text Add to dashboard Cite

show abstract

“…Inhalation Numerous, including pancreas [50], pancreas-kidney [51], heart [52], liver [53], and lung [54] No Horses, swine [75,76] and HSC [77] No Cattle [85] and kidney [86][87][88] No Rodents, cattle…”

Section: Rhodococcus Equimentioning

confidence: 99%

“…The "kennel cough" live vaccine, which contains a mixture of parainfluenza virus and B. bronchiseptica, has the potential to cause human B. bronchiseptica infection [134]. Rhodococcus equi has been increasingly documented as a pulmonary pathogen in transplant recipients [135], as well as an agent of unusual infection, including cerebral infection in a heart transplant recipient [52], pericarditis in a kidney transplant recipient [136], and vertebral osteomyelitis in a liver transplant recipient [53]. Cases of tularemia (due to Francisella tularensis infection) after both HSCT and renal transplantation have been reported [33][34][35].…”

Section: Bacterial Infectionmentioning

confidence: 99%

Zoonoses in Solid-Organ and Hematopoietic Stem Cell Transplant Recipients

Kotton

2007

Clinical Infectious Diseases

139

105

View full text Add to dashboard Cite

Numerous reports exist of the transmission of zoonoses to humans during and after solid-organ and hematopoietic stem cell transplantation. Donor-derived infections of numerous etiologies, including West Nile virus infection, Chagas disease, toxoplasmosis, rabies, lymphocytic choriomeningitis virus infection, and infection due to Brucella species have been reported. Most zoonoses occur as a primary infection after transplantation, and immunocompromised patients are more likely to experience significant morbidity and mortality from these infections. Risks of zoonotic infection in the posttransplantation period could be reduced by patient education. Increased recognition of the risks of zoonoses, as well as the advent of molecular biology-based testing, will potentially augment diagnostic aptitude. Documented zoonotic infection as it affects transplantation will be the primary focus of this review.

show abstract

“…Rhodococcus equi is well recognized as a cause of infection in humans and animals and is associated with a range of clinical manifestations, especially cavitating pneumonia in immunocompromised individuals, such as recipients of solid organ transplants and those with AIDS [1], although infection in apparently immunocompetent persons also has been reported [8]. Osteomyelitis associated with the bacterium appears to be very uncommon in humans [3,6]. Human infection associated with species of Rhodococcus other than R equi is infrequently reported.…”

Section: Introductionmentioning

confidence: 99%

Case Report: Rhodococcus erythropolis Osteomyelitis in the Toe

Roy¹,

Sidhom²,

Kerr³

et al. 2009

Clinical Orthopaedics &Amp; Related Research

View full text Add to dashboard Cite

The Rhodococcus species rarely cause musculoskeletal infections, with only two cases reported in the literature. We report the case of a 53-year-old woman who had an infection develop after first metatarsophalangeal joint fusion. A year after surgery, she continued to have pain and swelling with nonunion. She underwent revision of the arthrodesis and tissue samples from surgery revealed Rhodococcus erythropolis. The patient's symptoms improved with oral antibiotics. One year after the revision surgery, the fusion had united. We believe this is the first report of a case of a musculoskeletal infection caused by Rhodococcus erythropolis.

show abstract

Vertebral Osteomyelitis Due to Rhodococcus equi in a Liver Transplant Recipient

Cited by 26 publications

References 15 publications

Update and actual trends on bacterial infections following liver transplantation

Update and actual trends on bacterial infections following liver transplantation

Zoonoses in Solid-Organ and Hematopoietic Stem Cell Transplant Recipients

Case Report: Rhodococcus erythropolis Osteomyelitis in the Toe

Contact Info

Product

Resources

About