Vertebroplasty and Kyphoplasty

Lavelle, William F.; Carl, Allen L.; Lavelle, Elizabeth Demers; Khaleel, Mohammed A.

doi:10.1016/j.anclin.2007.07.011

Cited by 58 publications

(18 citation statements)

References 61 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Unfortunately, much of the current literature reports retrospective and case studies. There are limited data comparing balloon kyphoplasty versus vertebroplasty [4,10,[13][14][15][16]. The present study independently performed a prospective, comparative, and randomized clinical study to determine the effectiveness of vertebroplasty and kyphoplasty in treating symptomatic VCFs as well as to assess some clinical outcomes.…”

Section: Discussionmentioning

confidence: 99%

Balloon kyphoplasty versus vertebroplasty for treatment of osteoporotic vertebral compression fracture: a prospective, comparative, and randomized clinical study

et al. 2009

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Balloon kyphoplasty versus vertebroplasty for treatment of osteoporotic vertebral compression fracture: a prospective, comparative, and randomized clinical study

et al. 2009

View full text Add to dashboard Cite

show abstract

“…Experienced staff interventional neuroradiologists at our hospital performed all of the procedures (vertebroplasty and kyphoplasty) using standard methods 12. Procedures were performed with MAC anesthesia or using intravenous conscious sedation.…”

Section: Methodsmentioning

confidence: 99%

Palliation of compression fractures in cancer patients by vertebral augmentation: a retrospective analysis

Jha

Hirsch

Yoo

et al. 2010

J NeuroIntervent Surg

View full text Add to dashboard Cite

AimTo evaluate the efficacy of vertebral augmentation (VA) in cancer patients. Materials and methods From a retrospectively compiled database, 147 cancer cases (236 levels) were treated with VA. Mean age was 71612 years and 56.5% were female. Variables evaluated include age, sex, procedure type, vertebral level treated, number of levels treated per procedure and technical approach. Outcomes were assessed by a previously described method retrospectively applied from medical records: a binary system of 'responders' versus 'non-responders' and further subcategorization with a four level pain scale. Two patient groups were analyzed: (1) 147 cancer patients with either osteoporotic or malignant vertebral compression fractures (all compression fractures (ACFs)) and (2) 102 cases with documented metastatic compression fractures (MCFs). Univariate and multivariate analyses determined outcomes. Results 93% of MCFs and 88.5% of ACFs showed response to treatment (pain improvement or resolution): 30% of ACFs and 31% of MCFs experienced pain resolution. MCFs showed increasing age to be a predictor of response to treatment in univariate (OR¼1.79, p¼0.04) and multivariate (OR¼2.05, p¼0.03) analysis. In ACFs, bipedicular needle approach decreased the odds of pain resolution (OR¼0.28, p¼0.01). In MCFs, lung cancer (OR¼0.06, p¼0.03) and multiple myeloma (OR¼0.10, p¼0.01) decreased the odds of pain resolution. Conclusions VA provides pain relief for a majority of ACFs and MCFs. Increasing age may be predictive of pain relief outcomes in MCFs. There are special planning, imaging and technical considerations (eg, needle placement) in using VA to treat cancer patients.

show abstract

“…Kyphoplasty, first performed in 1998, has the additional step of using a balloon to form a cavity within the vertebral body to increase height, before injection of bone cement (3). The latter was developed to reduce the high pressure used to inject the cement and the fear of cement leakage onto delicate nerves just outside the vertebral body and increased fracture risk of neighboring vertebral bodies (4). Several studies have suggested that kyphoplasty has added advantages of restoration of vertebral height and correction of "hunchback" deformity as well as less risk of cement leakage (3).…”

Section: Two Thirds Of Acute Symptomatic Vertebral Fractures Improve mentioning

confidence: 99%

“…This progressive loss of bone density accelerates with age and affects more than 28 million Americans (2). Over 750,000 compression fractures of the spine occur in the United States every year (1,4). Loss of bone mass leads to acute and chronic pain syndromes, bony deformity, nerve compression, diminished quality of life, and increased morbidity and mortality.…”

Section: Answermentioning

confidence: 99%