Verteporfin Therapy for Choroidal Hemangioma: A Long-Term Follow-Up

Abstract

Persistent and complete absence of choroidal hemangioma associated with persistent improvement in visual acuity and central visual fields can be obtained with verteporfin PDT.

Tratamiento mediante terapia fotodinámica del hemangioma coroideo circunscrito

“…En los últimos años se ha descrito la TFD como una alternativa exitosa para tratar a estos pacientes [1][2][3][4] . La terapia actúa de forma selectiva sobre el endotelio vascular, respeta el resto de estructuras y su yatrogenia es menor que la de otros tratamientos 2 .…”

“…En general una única aplicación que cubra la totalidad del tumor suele ser suficiente 3 . Esta opción, utilizada en los pacientes de esta serie, resulta más económica y menos engorrosa para los pacientes.…”

25th RCOphth Congress, President's Session paper: 25 years of progress in medical retina

“…This technique has been shown to be effective in certain cases of CNV but is not currently in widespread use. 36 PDT has also been used and shown to be effective in the treatment of choroidal haemangioma, 37 chronic central serous retinopathy, 38 and in polypoidal vasculopathy, where it has been shown to be superior to ranibizumab. 39 Anti-angiogenic agents in AMD Anti-angiogenic therapy has transformed the treatment in wet AMD, with improved visual outcomes over PDT monotherapy, and ranibizumab and bevacizumab are currently the gold-standard care.…”

Congenital vascular malformations of the retina and choroid

“…PDT is now the preferred treatment in most centres. [44][45][46][47] This yields excellent anatomical and functional results with minimal risk of complications ( Figure 9). The exact treatment parameters of PDT are still debated but several authors have recommended bolus injections of Verteporfin, increased application time of laser energy, and overlapping treatment spots.…”

“…The exact treatment parameters of PDT are still debated but several authors have recommended bolus injections of Verteporfin, increased application time of laser energy, and overlapping treatment spots. [45][46][47] However, over-zealous treatment may cause complications such as RPE atrophy and secondary polypoidal choroidal vasculopathy. 48,49 Recent studies suggest that satisfactory results can be achieved using the same treatment settings as for exudative agerelated macular degeneration ( Figure 9).…”