Students may experience various types of headaches, as well as stress,
which can have an impact on their mental and social health as well as
their academic performance. Headache is one of the most common aspects
of modern life, owing to the rapid changes in human life. Students are
subjected to academic stress as a result of academic tests, homework
assignments, and other school requirements. Scientists are testing drugs
based on medical therapies based on previous research. Many drugs, such
as naproxen, flurbiprofen, fenoprofen, ketoprofen, and ibuprofen are
listed in the recommendations. Topological index is a molecular
descriptor that use to analyze the chemical and physical properties of
chemical compounds and can be used in modeling to predict the
physicochemical properties and biological activities of molecules in a
quantitative structure-property relationship (QSPR) and quantitative
structure-activity relationship (QSAR) studies. In this study,
M-polynomial methods were used to investigate several degree-based
topological indices for some drugs used for headaches (i.e., naproxen,
flurbiprofen, fenoprofen, ketoprofen, and ibuprofen). Furthermore, a
QSPR relationship was discovered between the various topological indices
and the various physicochemical properties of these antiviral drugs.
According to the obtained results, topological indices have a strong
correlation with the physicochemical properties of potential drugs.