Vertigo with dysautonomia and serious allergy: An unusual case of juvenile Ménière's disease

Wu, Haiyan; Gao, Zhiqiang

doi:10.1016/j.ijporl.2015.09.026

Cited by 7 publications

(4 citation statements)

References 19 publications

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“…This case differs from the first one because FA realizes with an IgE-dependent mechanism, linked to a positivity of food allergens SPT and RAST, while in the first case the pathogenic mechanism was non-IgE mediated. This is a novel literature finding as the only clinical report in childhood on the association between allergy and PNS involvement has been described by Wu and Gao,[19] in a 13-year-old male child with frequent episodes of vertigo and otologic symptoms. In this case, a Ménière's disease was diagnosed but failed to respond to conventional treatment.…”

Section: Discussionmentioning

confidence: 62%

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Nervous system involvement in clinical peripheral inflammation: A description of three pediatric cases

et al. 2016

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Latest research data have emphasized the interaction between the nervous and the immune systems. In this regard, it has been demonstrated that the disruption of the blood–brain barrier (BBB) secondary to peripheral inflammation may play a key role in this relationship. This assumption is linked to recent findings according to which units that constitute the BBB are not only simply neurologic but have also been reconsidered as “neurovascular” elements, through which immune system molecules are vehiculated within the central nervous system (CNS). Herein, we report two cases of food allergy (FA) and one case of infective gastroenteritis, associated with a spectrum of neurologic disorders involving both the CNS and the peripheral nervous system (PNS), postulating some etiopathogenic hypotheses to explain the link between peripheral inflammation and diseases of the nervous system (NS). Three pediatric cases of secondary NS involvement after gastrointestinal (GI) inflammation of different nature have been reported. The first case highlights the link between FA and CNS; the second one is based on a description of a link between GI infection and CNS involvement while the third one describes the relationship between FA and PNS. The importance of these reports relies on the clinical demonstration of a link between the immune system and the NS. The relationship between immune system and NS seems to have pleiotropic aspects, involving different areas of the NS, such as CNS and PNS, which also seem to be in some way interconnected.

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Section: Discussionmentioning

confidence: 62%

“…The authors therefore concluded that the autonomic nerves and the immune system could interact. [19]…”

Section: Discussionmentioning

confidence: 99%

Nervous system involvement in clinical peripheral inflammation: A description of three pediatric cases

et al. 2016

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“…Since the first report of pediatric MD in 1940, there have been relatively few cases reported in the literature. Meyerhoff documented nine cases of pediatric MD treated with endolymphatic sac drainage procedure to assess its safety and efficacy ( 25 ). Nevertheless, the efficacy of this surgery in pediatric patients remains contentious due to developmental and pathophysiological differences compared to adults.…”

Section: Discussionmentioning

confidence: 99%

Pediatric Ménière’s disease with disassociated cochlear and vestibular symptoms: a case report

Xu,

Li,

et al. 2024

Transl Pediatr

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Background Typical Ménière’s disease (MD) rarely occurs in childhood. Compared to adults, age-associated changes in vestibular function can occur during infancy and childhood. Previous case reports may have lacked some audiovestibular tests in children. It is worthwhile to follow a child with MD to observe how vertigo and hearing loss could progress under an insufficient vestibular system. Case Description A 14-year-old pediatric patient with disassociated episodes between vertigo and hearing loss was finally diagnosed with MD. He was diagnosed with probable MD due to lack of objective evidence of hearing loss in his first two admissions. However, in his third admission, he had hearing loss even without attack of vertigo and was finally diagnosed. By listing the patient’s audiovestibular auxiliary tests in a chronological order, we might follow the progress of pediatric MD. Gadolinium-enhanced magnetic resonance imaging (Gd-MRI) might be sensitive to reflect endolymphatic hydrops (EH). Medications including corticosteroids might be effective for both hearing loss and vertigo. Conclusions In pediatric MD, vestibular and cochlear symptoms may occur and progress independently. Audiovestibular evaluation, especially caloric tests and cervical vestibular evoked myogenic potential (cVEMP), can be useful for pediatric MD. Gd-MRI can be sensitive for detecting EH. Both systemic and postauricular administration of corticosteroids might be effective in alleviating vertigo and improving hearing. Prolongation of the follow-up period of pediatric MD is warranted.

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“…11 Localized symptoms such as lip swelling are not seen in those specific food allergy cases, making a scorpion allergy unlikely. 12,13…”

Section: Discussionmentioning

confidence: 99%

Neurological Symptoms From a Lollipop?

Levenbaum

Merte

Philip

2018

Clin Pediatr (Phila)

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Vertigo with dysautonomia and serious allergy: An unusual case of juvenile Ménière's disease

Cited by 7 publications

References 19 publications

Nervous system involvement in clinical peripheral inflammation: A description of three pediatric cases

Nervous system involvement in clinical peripheral inflammation: A description of three pediatric cases

Pediatric Ménière’s disease with disassociated cochlear and vestibular symptoms: a case report

Neurological Symptoms From a Lollipop?

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