Vertr�glichkeitsuntersuchungen von Holz im Knochengewebe

Kristen, H.; Bösch, Peter; H, Bednar; Plenk, H.

doi:10.1007/bf00414821

Cited by 12 publications

(2 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…While in the studies of Kristen et al (1977Kristen et al ( , 1979 direct bone contacts to wood surfaces could be shown, no direct bone contact, but only a foreign body response was observed at the cellulose interfaces in your referenced study of Gross et al (1992). Thus, the Gross et al (1992) cellulose material, as well as the PLA-PGA materials, are not "osteoconductive" in my understanding.…”

Section: H Plenkmentioning

confidence: 92%

“…Were the authors aware of the studies by Kristen et al (1977Kristen et al ( , 1978, and later by the people in Leiden (Li et al, 1997a,b) on bone reactions to wood, and that mineralization occurs naturally in several species of wood? Authors: We are well aware of those studies and they are thoroughly discussed in our previous papers concerning mineralization studies of cellulose in SBF (references are provided in the introduction).…”

Section: H Plenkmentioning

confidence: 99%

See 1 more Smart Citation

Mineralization of regenerated cellulose hydrogels induced by human bone marrow stromal cells

Granja¹,

Jeso²,

Bareille³

et al. 2005

eCM

View full text Add to dashboard Cite

The proliferation of cultured human bone marrow stromal cells (HBMSC) on regenerated cellulose hydrogels was assessed. Regenerated cellulose hydrogels showed good rates of HBMSC proliferation, the cells exhibiting a flattened morphology, and after 22 days in culture, the cells had homogeneously colonized the surface of the materials. Moreover, since the early days in culture, between the surface of the materials and attached cells a continuous granulated hydroxyapatite layer was formed. It has been previously demonstrated in vitro, but without cells, that these materials did not mineralize. Hence, it seems that HBMSC promoted the mineralization of the surface.

show abstract

Section: H Plenkmentioning

confidence: 92%

Section: H Plenkmentioning

confidence: 99%

Mineralization of regenerated cellulose hydrogels induced by human bone marrow stromal cells

Granja¹,

Jeso²,

Bareille³

et al. 2005

eCM

View full text Add to dashboard Cite

show abstract

Juniper wood as a possible implant material

Gross

Ezerietis

2003

J Biomedical Materials Res

View full text Add to dashboard Cite

Natural materials, such as wood and bone, possess structures fulfilling the requirements of support and transport of nutrients. Similarity in function and properties provides inspiration for investigating the possible use of wood as an implant material. Juniperus communis wood is dense, durable, and strong and has naturally impregnated essential oils that display antiseptic properties. This study investigated the toxicity of the oil, the effect of sterilization on the mechanical properties of the wood, and bone attachment with animal studies. The possible toxicity of the oil was determined orally and by intravenous injection. At low concentrations, the dose that would be released by the wood in the body could be tolerated without any detrimental effects. Sterilization of the wood in boiling water lowered the elastic modulus and modulus of rupture to a level at which the elastic modulus could be better matched to bone. Wood shaped into the form of femoral implants were implanted into rabbits and displayed good acceptance by the body up to a period of 3 years, indicating bone apposition, abutment into pores, and growth into drilled cavities.

show abstract

Natural composite of wood as replacement material for ostechondral bone defects

et al. 2007

View full text Add to dashboard Cite

Deciduous wood, birch, pretreated by a technique combining heat and water vapor was applied for the reconstruction of bone defects in the knee joint of rabbits. It was observed that wood showed characteristic properties to be incorporated by the host bone during observation time of 4, 8, and 20 weeks. The natural channel structure of wood served as a porous scaffold, allowing host bone growth as small islets into the wood implants. The other properties of heat-treated wood, such as bioactivity, good handling properties, and sufficient biomechanical properties, might be additional favorable factors for the application of wood as a natural composite material for bone and cartilage repair. At the interface of the surfaces of wood and living bone, bonding occurred. The Chemical Interface Model for bonding bone to wood consists of the reactive ions, such as hydroxyl groups --OH, and covalent bonding as well as hydrogen bonding, which originate from both wood and bone. The bone tissue trauma, with its reactive Ca(2+) and PO(4) (3-) ions, proteins, and collagen, available for interaction at ionic and nanolevel, are associated with the complicated chemistry in the cellular response of the early bone healing process. It was concluded that heat-treated wood acted like a porous biomaterial scaffold, allowing ongrowth and ingrowth of bone and cartilage differentiation on its surface, and demonstrating osteoconductive contact, bonding at the interface.

show abstract

Vertr�glichkeitsuntersuchungen von Holz im Knochengewebe

Cited by 12 publications

References 7 publications

Mineralization of regenerated cellulose hydrogels induced by human bone marrow stromal cells

Mineralization of regenerated cellulose hydrogels induced by human bone marrow stromal cells

Juniper wood as a possible implant material

Natural composite of wood as replacement material for ostechondral bone defects

Contact Info

Product

Resources

About