Very good inter-rater reliability of Engel and ILAE epilepsy surgery outcome classifications in a series of 76 patients

Durnford, Andrew; Rodgers, William H.; Kirkham, Fenella J.; Mullee, Mark; Whitney, Andrea; Prevett, Martin; Kinton, Lucy; Harris, Matthew J; Gray, William Peter

doi:10.1016/j.seizure.2011.08.004

Cited by 86 publications

(64 citation statements)

References 9 publications

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“…” Seizure frequency, the most commonly monitored aspect of disease state by physicians, is an often used marker of epilepsy (disease) severity and treatment success. In fact, it is the basis of the popular Engel classification of seizure outcomes used for surgery and the derivative ILAE seizure outcome classification . Seizures are the target of epilepsy therapies, and for most purposes, seizure frequency appears to be an adequate outcome measure.…”

Section: Introductionmentioning

confidence: 99%

Seizure burden in severe early‐life epilepsy: Perspectives from parents

et al. 2019

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Objectives Seizure burden is typically measured by seizure frequency yet it entails more than seizure counts, especially for people with severe epilepsies and their caregivers. We aimed to characterize the multi‐faceted nature of seizure burden in young people and their parents who are living with severe early‐life epilepsies. Methods A one‐day workshop and a series of teleconferences were held with parents of children with severe, refractory epilepsy of early‐life origin and providers for children with epilepsy. The workshop sessions were structured as focus groups and aimed to identify components of seizure burden and their impact from the perspective of parents and providers. Data were gathered, organized, and refined during the workshop using an iterative 4‐step process that drew upon grounded theory. Results Three primary components of seizure burden were identified: frequency, severity, and unpredictability, which was as important if not more important at times than frequency and severity. Caregivers noted that the impacts of seizures were experienced as acute‐immediate consequences, longer‐term consequences, and as chronic effects that develop and evolve over time. The severity of the child's neurological and medical status as well as where in the disease journey a family was represented additional contextual factors that influenced the experience of seizure burden. Significance Patient‐reported and patient‐centered outcomes are increasingly incorporated into the evaluation of treatment effectiveness. Without understanding how the disease creates burden for the patient (or family), it is difficult to know how to assess the impact of treatment. Our preliminary findings indicate seizure burden is a complex construct and unpredictability can be as important as frequency and severity.

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Section: Introductionmentioning

confidence: 99%

Seizure burden in severe early‐life epilepsy: Perspectives from parents

et al. 2019

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“…In this system, seizure outcome is based on the number of seizure events a patient experiences postoperatively. Further, they have both been shown to have excellent inter-rater reliability and have been found to be comparable to each other (Durnford et al 2011 ) . Criticisms of this system include the use of ambiguous terms like "disabling seizures," "almost seizure-free," and "worthwhile improvement" (Wieser et al 2001 ) .…”

Section: Appendix 91: Neurovascular Websites For Parentsmentioning

confidence: 88%

“…RE typically only involves one hemisphere, although bilateral involvement has been reported (Bien et al 2005 ;Dubeau 2011 ) . It was fi rst described in 1958 by Theodore Rasmussen and his colleagues.…”

Section: Rasmussen's Encephalitismentioning

confidence: 99%

Nursing Care of the Pediatric Neurosurgery Patient

Hickey

2013

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“…The postoperative outcome was assessed according to a classification adapted from the ILAE. Seizure-free patients without auras, seizure-free patients with postoperative auras, and patients with fewer than three seizures per year were considered to be favorable outcomes based on the recommendations of the ILAE commission report [17, 18]. …”

Section: Discussionmentioning

confidence: 99%

Epilepsy Surgery Series: A Study of 502 Consecutive Patients from a Developing Country

Alsemari

Alotaibi

Baz

et al. 2014

Epilepsy Research and Treatment

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Purpose. To review the postoperative seizure outcomes of patients that underwent surgery for epilepsy at King Faisal Specialist Hospital & Research Centre (KFSHRC). Methods. A descriptive retrospective study for 502 patients operated on for medically intractable epilepsy between 1998 and 2012. The surgical outcome was measured using the ILAE criteria. Results. The epilepsy surgery outcome for temporal lobe epilepsy surgery (ILAE classes 1, 2, and 3) at 12, 36, and 60 months is 79.6%, 74.2%, and 67%, respectively. The favorable 12- and 36-month outcomes for frontal lobe epilepsy surgery are 62% and 52%, respectively. For both parietal and occipital epilepsy lobe surgeries the 12- and 36-month outcomes are 67%. For multilobar epilepsy surgery, the 12- and 36-month outcomes are 65% and 50%, respectively. The 12- and 36-month outcomes for functional hemispherectomy epilepsy surgery are 64.2% and 63%, respectively. According to histopathology diagnosis, mesiotemporal sclerosis (MTS) and benign CNS tumors had the best favorable outcome after surgery at 1 year (77.27% and 84.3%, resp.,) and 3 years (76% and 75%, resp.,). The least favorable seizure-free outcome after 3 years occurred in cases with dual pathology (66.6%). Thirty-four epilepsy patients with normal magnetic resonance imaging (MRI) brain scans were surgically treated. The first- and third-year epilepsy surgery outcome of 17 temporal lobe surgeries were (53%) and (47%) seizure-free, respectively. The first- and third-year epilepsy surgery outcomes of 15 extratemporal epilepsy surgeries were (47%) and (33%) seizure-free. Conclusion. The best outcomes are achieved with temporal epilepsy surgery, mesial temporal sclerosis, and benign CNS tumor. The worst outcomes are from multilobar surgery, dual pathology, and normal MRI.

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Very good inter-rater reliability of Engel and ILAE epilepsy surgery outcome classifications in a series of 76 patients

Cited by 86 publications

References 9 publications

Seizure burden in severe early‐life epilepsy: Perspectives from parents

Seizure burden in severe early‐life epilepsy: Perspectives from parents

Nursing Care of the Pediatric Neurosurgery Patient

Epilepsy Surgery Series: A Study of 502 Consecutive Patients from a Developing Country

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