Very Late-Onset Corneal Scarring After Photorefractive Keratectomy Induced by Cataract Surgery

Fischinger, Isaak; Zapp, Daniel; Seiler, Theo

doi:10.3928/1081597x-20160121-06

Cited by 2 publications

(3 citation statements)

References 16 publications

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“…Late onset corneal haze in eyes with previous PRK has been reported with intervals varying from two to 20 years, following different stimuli, from cataract surgery, LASIK and vitreoretinal surgery to blunt trauma, corneal infections and UV-light exposure. 1 , 9 Despite the widespread use of ICRS in different scenarios, corneal haze has not been previously reported after its use in virgin eyes except from the mild subepithelial haze that occurs around the ring and tends to disappear in the following months. 10 The occurrence of haze after ICRS in an eye with a long-time history of PRK supports the evidence that permanent corneal wound healing changes occur after PRK.…”

Section: Discussionmentioning

confidence: 99%

“…Photorefractive keratectomy (PRK) is a technique used to correct myopia, hyperopia and astigmatism for over 30 years. 1 Corneal wound healing process following PRK is a complex inflammatory cascade eventually leading to some degree of anterior subepithelial haze. 2 Mild haze usually appears between one and three months after surgery and does not cause clinical symptoms.…”

Section: Introductionmentioning

confidence: 99%

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Late-onset corneal haze after intrastromal corneal ring implantation in an eye with previous topography-guided PRK

Piccinini

Ghanem

2020

American Journal of Ophthalmology Case Reports

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Purpose To report a case of late-onset corneal haze 3 months after intrastromal corneal ring segment (ICRS) implantation in an eye with previous transepithelial topography-guided photorefractive keratectomy (TG-PRK). Observations A 40-year-old woman with stable keratoconus for 10 years underwent limited TG-PRK with mitomycin C in both eyes for mixed astigmatism. After four years, with atopic symptoms worsening and eye rubbing, the patient presented keratoconus progression in the left eye with increased irregular astigmatism. An ICRS was implanted with initial improvement in vision. Three months later severe subepithelial haze was observed along the ring groove. Conclusion and importance This is the first report of subepithelial haze after ICRS implantation. This report increases the evidence that permanent corneal wound healing changes occur after PRK and that late-onset haze may be triggered by corneal remodeling, as little inflammation or epithelial defect occurs after ICRS implantation. We do believe the detection of triggers, identification of risk factors of late-onset haze and appropriate preoperative counselling have an increasing importance due to the rising number of patients that have undergone PRK.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Late-onset corneal haze after intrastromal corneal ring implantation in an eye with previous topography-guided PRK

Piccinini

Ghanem

2020

American Journal of Ophthalmology Case Reports

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“…Одной из первых лазерных технологий, внедренных в клиническую практику в 1990-е гг., была фоторефракционная кератэктомия (ФРК), на сегодняшний момент на долю этой операции приходится 5-7% от общего числа всех рефракционных операций [1]. [4,5]. Период восстановления требует значительной медикаментозной поддержки, назначение кортикостероидов может спровоцировать подъем внутриглазного давления [6].…”

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Femtosecond Lenticular Extraction via Small Access in the Correction of Residual Myopia After Photorefractive Keratectomy

Pisarevskaya¹,

Schuko²,

Ivleva³

2021

СПНО (MPSE)

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Целью данной работы является оценка структурного и функционального эффекта коррекции остаточной миопии методом фемтосекундной экстракции лентикулы роговицы через малый доступ у пациентов, ранее оперированных по технологии фоторефракционной кератэктомии (ФРК). В исследование включены пациенты с остаточной миопией слабой степени после операции ФРК, которым докоррекция выполнялась с помощью фемтосекундной экстракции лентикулы роговицы через малый доступ. Оценка изменения параметров роговицы и зрительных функций проводилась до и после операции с кратностью 1 день, 1 месяц, 3 и 6 месяцев. В первые сутки после операции некорригируемая острота зрения вдаль составила 0,94±0,11, рефракция цели ±0,25 дптр достигнута в 98% случаев, цилиндрический компонент ±0,5 дптр -в 96% случаев. К 6 месяцам острота зрения 0,8 и выше получена в 100% случаев, 1,0 и выше -в 79%, с достижением рефракции цели ±0,5 дптр -в 99% случаев. Клинические результаты коррекции резидуальной миопии методом фемтосекундной экстракции лентикулы роговицы через малый доступ у пациентов, ранее оперированных по технологии ФРК, свидетельствуют о том, что предложенная технология докоррекции остаточной миопии является высокоэффективной и безопасной в случаях отсутствия фиброплазии или при наличии помутнений, денситометрическая плотность которых не превышает 35 единиц. Ключевые слова: фемтосекундный лазер, фоторефрактивная кератэктомия, субэпителиальная фиброплазия роговицы, денситометриия, ReLEX SMILE.

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Very Late-Onset Corneal Scarring After Photorefractive Keratectomy Induced by Cataract Surgery

Abstract: A few cases of late-onset corneal scarring after PRK have been described in the literature following trauma or ophthalmic surgery. Due to the need for cataract surgery in an aging population with previous PRK, this might become a more common problem.

Cited by 2 publications

References 16 publications

Late-onset corneal haze after intrastromal corneal ring implantation in an eye with previous topography-guided PRK

Late-onset corneal haze after intrastromal corneal ring implantation in an eye with previous topography-guided PRK

Femtosecond Lenticular Extraction via Small Access in the Correction of Residual Myopia After Photorefractive Keratectomy

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