Very low dose quetiapine‐induced galactorrhea in combination with venlafaxine

Venlafaxine-Associated Euprolactinemic Galactorrhea and Hypersexuality

“…4 However, more rare side effects have also been described, including painful ejaculation, 5 hypersexuality and spontaneous erections, 6-8 gynecomastia, 9 mastalgia, 10 and galactorrhea. [11][12][13][14] Multiple antidepressants, particularly those with demonstrated capacity to inhibit serotonin reuptake, have been shown to commonly adversely affect libido, sexual arousal, and orgasm, and it is thought that this is caused primarily by a disruption in mesolimbic dopamine activity mediated by serotonin-2 (5-HT 2 ) agonism. However, in this patient, sexual desire was actually substantially increased, the first time this has been documented in the literature in a female patient.…”

Low dose quetiapine induced galactorrhoea: a case report

“…However, it did not report any consequent galactorrhoea. Pae et al present a report of quetiapine and venlafaxine leading to galactorrhoea [10]. They focus on the role of venlafaxine on dopamine and the consequent galactorrhoea.…”

“…One case report of galactorrhoea associated with quetiapine [10], focused on the role of venlafaxine and its action on dopamine in the brain.…”