Very small air bubbles (10 – 70 μl) cause clinically significant variability in syringe pump fluid delivery

Davey, Chris; Stather-Dunn, T

doi:10.1080/03091900500067801

Cited by 10 publications

(6 citation statements)

References 20 publications

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“…It is a common observation to find bubbles in cardiac chambers following most intravenous infusions. 20 Furthermore, VGE during foam sclerotherapy is probably a very common event. 21 Circulating bubbles derived from the injected foam have not been shown to possess sclerosing activity.…”

Section: Discussionmentioning

confidence: 99%

Venous gas embolism during foam sclerotherapy of saphenous veins despite recommended treatment modifications

Parsi

2010

Phlebology

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Section: Discussionmentioning

confidence: 99%

Venous gas embolism during foam sclerotherapy of saphenous veins despite recommended treatment modifications

Parsi

2010

Phlebology

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“…In a recent systematic review, Snijder et al [14] noted mechanical compliance, resistance and dead volume as the three main causes of flow changes. Presence of air bubbles and vertical displacement of the SIP were also identified as causes of flow variability with a possible clinical effect [15, 16]. A comparable study on the effect of altitude on medical devices was conducted to assess the accuracy of ventilation devices in a simulated hypobaric situation [17].…”

Section: Discussionmentioning

confidence: 99%

Accuracy of low-weight versus standard syringe infusion pump devices depending on altitude

Blancher

Repellin

Maignan

et al. 2019

Scand J Trauma Resusc Emerg Med

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Background Intravenous drug infusions in critically ill patients require accurate syringe infusion pumps (SIPs). This is particularly important during transportation of critically ill patients by helicopter emergency medical services (HEMS), where altitude may influence device performance. Because weight is a real concern in HEMS, new low-weight devices are very appealing. The aim of this study was to compare infusion flow rates delivered by low-weight versus standard SIP devices, in the prehospital emergency medicine setting, at different altitudes. Methods We conducted a comparative bench study involving five SIP devices (two standard and three low-weight models) at 300, 1700 and 3000 m altitude. The primary endpoint was the flow rate delivered by SIPs for prespecified values. We used two methods to measure flow. The normative method consisted in measuring weight (method A) and the alternate method consisted in measuring instantaneous flow (method B). Results Using method A, no significant differences were found in median flow rates and interquartile range depending on device and altitude for a prespecified 10-mL/h flow. However, method B showed that low-weight SIPs delivered multiple sequential boluses with substantial variations (1.2–15.8 mL/h) rather than a prespecified continuous 5-mL/h flow. At 1700 m altitude, the interquartile range of delivered flows increased only for low-weight devices ( p for interaction< 0.001). Conclusions Despite satisfactory normative tests, low-weight SIPs deliver discontinuous flow with potential clinical implications for critically ill patients receiving vasoactive drugs. This study also highlights a thus far unknown negative impact of altitude on SIP function. We believe that normative requirements for SIP approval should be revised accordingly.

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“…Una de ellas es la remoción de burbujas del circuito de infusión. Se han realizado estudios que han demostrado que incluso la presencia de burbujas que impresionan como "clínicamente irrelevantes", tienen un impacto signifi cativo en el funcionamiento de las BIC 9,10 . En este estudio se evidenció que aproximadamente sólo el 50% de los encuestados considera esta medida al instalar una BIC.…”

Section: Discussionunclassified

Bombas de infusión continua de jeringa en unidades neonatales

2011

Rev. chil. pediatr.

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Continuous infusion pumps at neonatal intensive care units Introduction: Continuous Infusion pumps (CIP) are frequently used at neonatal intensive care units (NICUs), to administer medications at fl ow rates lower than 1 ml/H. Various factors have been shown to alter their performance. No studies have been completed in Chile in this area. Objectives: To describe frequent clinical practices to administer medications through CIP at NICUs in Chile, and suggest recommendations about it. Methods: Four professionals at NICUs in 19 centers were surveyed regarding syringe size, fl ow rate and precautions. Results: When starting countinuous infusion, 81.9% of surveyed professionals use 50 cc syringes, and 66.7% of them use fl ow rates under 1 ml/h. Main precautions include elimination of bubbles in the circuit (51.4%), review of conections (38.9%) and precise fi t between the syringe and the CIP (36.1%). Conclusions: In surveyed NICUs, low fl ow rates and 50cc syringes are frequently used to infuse medications. NICU staff must consider factors that affect the performance of CIP, prefer smaller syringes and fl ow rate over 1 ml/h for continuous infusion of drugs.

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Very small air bubbles (10 – 70 μl) cause clinically significant variability in syringe pump fluid delivery

Cited by 10 publications

References 20 publications

Venous gas embolism during foam sclerotherapy of saphenous veins despite recommended treatment modifications

Venous gas embolism during foam sclerotherapy of saphenous veins despite recommended treatment modifications

Accuracy of low-weight versus standard syringe infusion pump devices depending on altitude

Bombas de infusión continua de jeringa en unidades neonatales

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