Vesicle and Cell Networks:  Interconnecting Cells by Synthetic Polymers

Abstract

Water-soluble polymers carrying a small fraction of hydrophobic groups are able to insert these groups into the hydrophobic interior of lipid bilayers or membranes. Under certain conditions such polymers can interconnect different vesicles or biological cells. With increasing polymer concentration this leads to the formation of a three-dimensional network. In this paper we report about the preparation and a first characterization of the structure and the mechanical properties of these new vesicle-polymer and polymercell gels composed of R,ω-cholesterol-modified poly(oxyethylene) and dimethyldioctadecylammonium chloride vesicles or living cells.

DNA conformational dynamics in the presence of catanionic mixtures

“…E-mail: sergey.melnikov@unilever.com ously and reversibly and remain stable for a long period of time [15]. These systems are used in several pharmacological and personal care applications [4,16,17].…”

Effect of poly-α, γ, L-glutamic acid as a capping agent on morphology and oxidative stress-dependent toxicity of silver nanoparticles

“…37,38 The absorption peaks at around 1600-1690 cm -1 and 1395-1400 cm -1 were characteristic of amide groups and C=O groups. Glutamic acid, the building monomer of polyglutamic acid, possesses three chemically active functional groups, ie, α-NH 2 , α-COOH, and γ-COOH.…”

Macromolecular cell surface engineering for accelerated and reversible cellular aggregation

“…Please do not adjust margins biomaterials [37][38][39] for tissue regeneration or the formation of millimetre sized 3D tumoroids 40,41 for in vitro modelling applications. Strikingly, both copolymers could form macroscopic cell-laden gels under physiological conditions observable by the naked eye that could be reversibly turned to their corresponding sol state either by the addition of glucose (in the case of P1) or lowering the temperature (in the case of P2), as illustrated in Fig.…”