Vestibular evoked myogenic potentials in patients with diabetes mellitus

Abstract

Although the exact mechanism and most involved region of the vestibular system have not yet been fully clarified, vestibular dysfunction has been demonstrated in patients with diabetes mellitus (DM). Vestibular evoked myogenic potential (VEMP) is a short latency electromyographic response to sound or vibration stimuli that may reflect otolith organ or related reflex functions. Since its first description in 1992, VEMP has become a significant part of the vestibular test battery as an objective measurement tool. In diabetic patients, VEMP responses have been studied in order to determine any otolith organ or related reflex dysfunctions. Here, we review the literature with regard to VEMP findings representing any peripheral vestibular end-organ dysfunction in patients with DM. Distinctive vestibular end-organ impairments seem to be demonstrated in patients with DM either with or without DNP via objective vestibular testing tools including VEMP recordings according to relevant studies. However, further studies with larger sample sizes are required to reveal the more definitive findings of VEMP recordings regarding the vestibular pathologies in patients with DM.

Vestibular Nerve Function In Patients With Type 2 Diabetes Detected By Vestibular Evoked Myogenic Potentials

“…Another study [17] found that diabetes causes degeneration and pathological alterations of vestibular type I hair cells in the microvascular end organs of diabetic rats, and hyperglycemia-induced metabolic stress can cause loss of type 1 hair cells in the balloon and cochlear nerve myelinolysis. In addition, vestibulocochlear nerve damage in diabetic rats has been demonstrated, including myelin lamina rupture and myelin thinning.…”

The effect of the severity of COVID-19 on the sequelae of the audiovestibular system

“…In people older than 60 years, VEMP responses may indicate alterations. 13,14 Therefore, we excluded patients with conductive hearing loss and sensorineural hearing loss, although it is known that sensorineural hearing loss does not affect the results of VEMP. The p13-n23 amplitude differed significantly between the groups in the right ear c-VEMP results.…”