Vestibular Impairments on Objective Diagnostic Tests in HIV+ Women and Control Men and Women

Abstract

To describe the value of two vestibular test batteries across ages in healthy men and women for detecting vestibular disorders and to compare the occurrence of vestibular disorders in the healthy adult population and women with human immunodeficiency virus (HIV) disease.Study Design: Two groups were tested on the battery of objective diagnostic tests of the vestibular system. Setting: Two tertiary care centers. Subjects: Healthy controls (284 women and 105 men) and women ( 63) with HIV/AIDS (HIV+) who are being followed up in a longitudinal study of HIV. They were tested on objective diagnostic tests of the vestibular system.Results: In all age decades, healthy controls had evidence of vestibular impairment, significantly more in older adults. HIV+ subjects, all females, did not differ from healthy control females.Conclusion: These data suggest that at all ages, people do have decreased vestibular function, even young, asymptomatic, and apparently healthy adults. HIV disease, itself, does not cause an increased prevalence of peripheral vestibular disorders when HIV is controlled on antiretroviral medication.

A Retrospective Study of the Relationship Between Hypertension and Vestibular Disorders in Middle-Aged Women With and Without HIV

“…This retrospective study was conducted between February 2018 to March 2019 and included participants from the Georgetown University WIHS site who had previously participated in a study on vestibular functions [5]. The study included WIHS participants who were PLWH as well as age-matched controls (PLWOH subjects) with similar socioeconomic status.…”

“…For calorics, eye movements were recorded with infrared video-oculography. The collection of these measures was described previously [5]. The test outcomes were classified as normal or abnormal: bi-thermal caloric weakness (caloric; abnormal, bi-thermal caloric weakness ≥25%), cervical VEMP and bi-thermal caloric test plus VEMP (Caloric + VEMP).…”

“…Recent evidence has shown that stage 2 HTN is a predictor of abnormal results on objective tests of the VNG [4]. One study showed that the frequency of abnormal VNG responses did not differ between middle-aged women in both groups -PLWH and PLWOH [5]. In healthy controls and PLWH, people of all ages who did not complain of vertigo had evidence of vestibular impairment, although it was more common in older adults.…”

Ocorrência de sinais e sintomas otoneurológicos em pessoas vivendo com HIV/AIDS: Revisão integrativa

“…No entanto em um estudo transversal conduzido por Cohen et al (2021) com 262 mulheres com idades entre 21,9-87,6 anos, idade média de 49,6 anos, e 10,5 homens com idades entre 21,4-84,5 anos, idade média de 48,3 anos, revelou que mesmo os adultos jovens e de meia-idade apresentam muitas anormalidades, os autores propõe que mesmo os adultos jovens e de meia-idade que não procuram atendimento para os sintomas podem apresentar vertigem e problemas de equilíbrio, e os médicos que cuidam de adultos de todas as idades devem estar preparados para lidar com pacientes cujas queixas que são consistentes com distúrbios vestibulares.…”

Changes in Measures of Vestibular and Balance Function and Hippocampus Volume in Alzheimer’s Disease and Mild Cognitive Impairment

“…We wanted to be able to compare subjects in this study to individuals of the same age who did not have MCI or AD, and who had been tested in the same laboratory with the same equipment. Therefore, we compared the vestibular test findings from the new subjects to data from subjects who were previously tested in this lab (24). Details are provided in the Results.…”