Fighting Antimicrobial Resistance 2018
DOI: 10.5599/obp.15.7
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Veterinary antimicrobial stewardship

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Cited by 4 publications
(6 citation statements)
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“…It is well established that tetracycline resistance in the South African agricultural setting is high, which may be a reflection of the antibiotic practices in South Africa [ 34 , 65 , 66 ]. Tetracycline can be purchased over the counter and used at the farmer’s own discretion [ 67 ]. A previous study by the authors (2022) showed that tetracyclines were the antibiotic class used in the highest quantity (i.e., 453.65 ± 35.49 kg or 135.16 mg/kg ± 3.31 mg/kg) on the same farm, which will explain why tetracycline resistance was high (95.28%, 101/113) in porcine isolates and was predominantly mediated by the tet A and tet B genes [ 35 ].…”
Section: Discussionmentioning
confidence: 99%
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“…It is well established that tetracycline resistance in the South African agricultural setting is high, which may be a reflection of the antibiotic practices in South Africa [ 34 , 65 , 66 ]. Tetracycline can be purchased over the counter and used at the farmer’s own discretion [ 67 ]. A previous study by the authors (2022) showed that tetracyclines were the antibiotic class used in the highest quantity (i.e., 453.65 ± 35.49 kg or 135.16 mg/kg ± 3.31 mg/kg) on the same farm, which will explain why tetracycline resistance was high (95.28%, 101/113) in porcine isolates and was predominantly mediated by the tet A and tet B genes [ 35 ].…”
Section: Discussionmentioning
confidence: 99%
“…Strasheim and colleagues (2022) previously reported that olaquindox was the antibiotic class used in the second highest quantity (i.e., 258.33 ± 8.04 kg or 77.07 mg/kg ± 3.93 mg/kg) on the farm [ 35 ]. Antibiotic growth promotors are not banned in South Africa, and their use has well-documented consequences of co-selection of resistance toward other antibiotics, which may lead to co-transmission of multiple antibiotic resistance genes [ 67 , 70 ]. The use of olaquindox as a growth promotor should be reconsidered in the South African context, taking food security, economic productivity, animal welfare and the emergence of antibiotic resistance into account.…”
Section: Discussionmentioning
confidence: 99%
“…It is well established that tetracycline resistance in the South African agricultural setting is high, which may be a reflection on the antibiotic practices in South Africa [46][47][48]. Tetracycline can be purchased over the counter and used at the farmers own's discretion [49]. A previous study by the authors (2022) showed that tetracyclines were the antibiotic class used in the highest quantity (i.e., 453.65 ± 35.49 kg or 135.16 mg/kg ± 3.31 mg/kg) on the same farm, which will explain why tetracycline resistance was high (95.28%.…”
Section: Discussionmentioning
confidence: 99%
“…These antimicrobials which include, among others, growth promoters, antimastitis, anticoccidials and anthelminthics (i.e. sulphonamides, tetracyclines, macrolides, ionophores and streptogramins) are regulated by the stock remedies Act (Eagar & Naidoo, 2017; Naidoo & Eagar, 2019; Schellack et al., 2017). This is in contrast to countries like Sweden and Denmark where better controls are in place.…”
Section: Discussionmentioning
confidence: 99%