Viable Monkeypox virus in the environment of a patient room

Marimuthu, Kalisvar; Wong, Judith Chui Ching; Lim, Poh Lian; Octavia, Sophie; Huan, Xiaowei; Ng, Yi Kai; Yang, Junjing; Sutjipto, Stephanie; Linn, Kyaw Zaw; Setoh, Yin Xiang; Ong, Chong Hui Clara; Griffiths, Jane; Farhanah, Sharifah; Cheok, Thai Shawn; Sulaiman, Nur Ashikin Binti; Congcong, Sipaco Barbara; Neves, Erica Sena; Loo, Liang Hui; Hakim, Luqman; Sim, Shuzhen; Lim, Merrill; Nazeem, Mohammad; Vasoo, Shawn; Tham, Kwok Wai; Ng, Oon Tek; Ng, Lee Ching

doi:10.1101/2022.09.15.22280012

Cited by 5 publications

(2 citation statements)

References 15 publications

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“…It is currently thought that certain activities could cause the mpox virus to be suspended in the air 30 . Practices that could aerosolize virus particles, such as shaking bed linens or an aerosol‐generating procedure (such as intubation) 52 or such as opening of doors, 29 vacuum cleaning and transport of contaminated items for washing, 38 should be avoided; therefore, the need for healthcare professionals to wear the proper respiratory protection when conducting tasks that could cause infectious material to be suspended in polluted surroundings is essential 30 . Further studies are needed to evaluate the extent to which the presence of mpox virus DNA in the air could affect immunocompromised patients in healthcare facilities, and further epidemiological studies are crucial, especially in Africa.…”

Section: Type Sample Mpox Strain Used Referencesmentioning

confidence: 99%

Mpox virus Clade IIb detection in the air

Saied

2023

Journal of Medical Virology

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Mpox is a viral zoonotic disease endemic in Central and West Africa that is caused by the Mpox virus, which belongs to the Orthopoxvirus genus and Poxviridae family. The clinical manifestations of mpox infection are milder than those of smallpox, and the incubation time of mpox varies from 5 to 21 days. Since May 2022, the mpox outbreak (formerly known as monkeypox) has suddenly and unexpectedly spread in non-endemic countries, suggesting that there may have been some undetected transmissions. Based on molecular analysis, there are two major genetic clades that represent the mpox virus: Clade I (formerly the Congo Basin clade OR the Central African clade) and Clade II (formerly the West African clade). It is believed that people who are asymptomatic or paucisymptomatic may spread the mpox virus. Infectious viruses cannot be distinguished by PCR testing; therefore, virus culture should be carried out. Recent evidence regarding the detection of the mpox virus (Clade IIb) in air samples collected from the patient's environment during the 2022 mpox outbreak was reviewed. Further studies are needed to evaluate the extent to which the presence of mpox virus DNA in the air could affect immunocompromised patients in healthcare facilities, and further epidemiological studies are crucial, especially in Africa.

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Section: Type Sample Mpox Strain Used Referencesmentioning

confidence: 99%

Mpox virus Clade IIb detection in the air

Saied

2023

Journal of Medical Virology

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“…2 In support of such findings, viable mpox virus has been detected on various surfaces in home and hospital settings of infected individuals (Table 1). [3][4][5][6][7][8] One quantitative study of viable mpox virus in a residential setting found the highest level on underwear. 3 Viable mpox has been detected on household surfaces for up to 15 days, but at low titers suggesting a lesser potential for transmission.…”

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confidence: 99%