Vibro-Tactile Stimulation as a Non-Invasive Neuromodulation Therapy for Cervical Dystonia: A Case Study

Zhu, Yi

doi:10.1109/embc46164.2021.9629717

Cited by 2 publications

(1 citation statement)

References 29 publications

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“…Studies have shown that the application of vibration to head and neck muscles in ST patients resulted in an immediate and significant reduction in involuntary muscle activity[ 59 ]. Recent research indicates that following vibration therapy in patients with right torticollis, the frequency and severity of the disturbances in tension posture significantly reduced, suggesting its effectiveness in spasm treatment[ 60 ]. In clinical practice, during the early stages of treatment, patients may experience muscle tension triggered by vibratory stimulation.…”

Section: Vibration Therapymentioning

confidence: 99%

Research progress in spasmodic torticollis rehabilitation treatment

Zhang,

Zeng,

et al. 2024

World J Clin Cases

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Spasmodic torticollis (ST) is a focal dystonia that affects adults, causing limited muscle control and impacting daily activities and quality of life. The etiology and curative methods for ST remain unclear. Botulinum toxin is widely used as a first-line treatment, but long-term usage can result in reduced tolerance and adverse effects. Rehabilitation therapy, with its minimal side effects and low potential for harm, holds significant clinical value. This article explores the effectiveness of adjunctive therapies, including exercise therapy, transcranial magnetic stimulation, shockwave therapy, neuromuscular electrical stimulation, vibration therapy, electromyographic biofeedback, and acupuncture, in the treatment of ST. The aim is to provide clinicians with additional treatment options and to discuss the efficacy of rehabilitation therapy for ST.

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Section: Vibration Therapymentioning

confidence: 99%

Research progress in spasmodic torticollis rehabilitation treatment

Zhang,

Zeng,

et al. 2024

World J Clin Cases

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A Pilot Interventional Study on Feasibility and Effectiveness of the CUE1 device in Parkinson’s disease

Azoidou,

Rowsell,

Camboe

et al. 2024

Preprint

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Introduction: Current treatments for patients with Parkinson's disease (PwP) can fail to address gait disturbance and falls, which in turn affect quality of life (QoL). The CUE1 device delivers cueing with vibrotactile stimulation showing potential to alleviate motor symptoms and reduce falls based on preliminary user testing results. Objectives: To evaluate the feasibility, safety, and tolerability of CUE1 and its effect on motor and non-motor symptoms in PwP. Methods: PwP used the CUE1 for 9-weeks and were assessed at week 0, 3, 6, and 9 on MDS-UPDRS Part-III, Timed Up and Go (TUG), TUG with dual task (DT), Functional Gait Assessment (FGA), and Bradykinesia Akinesia Incoordination (BRAIN) test. Patients reported outcomes through MDS-UPDRS Part-I, -II, and -IV and Pittsburgh Sleep Quality Index (PSQI). Results: Ten PwP (5 females, age range: 46-80; disease duration: 3-9 years) completed the CUE1 intervention with 100% compliance and no adverse events. CUE1 comfort and usability were rated highly (80%). Immediate CUE1 effect was observed on MDS-UPDRS-III 45.40+/-12.22 vs 39.60+/-11.74, p=0.008), TUG(11.53+/-1.92 vs 11.08+/-1.94, p=0.022), TUG DT(18.57+/-5.75 vs 17.61+/-6.28, p=0.037) and FGA(16.40+/-3.86 vs 18.60+/-3.92, p=0.007). Cumulative effect was noted on MDS-UPDRS-III(45.40+/-12.22 vs 27.80+/-12.32, p=0.005), FGA(18.60+/-3.92 vs 23.10+/-2.85, p<0.001), TUG DT(18.57+/-5.75 vs 13.58+/-7.05, p=0.031), BRAIN kinesia (45.10+/-14.39 vs 42.10+/-12.74, p<0.001) and incoordination (24331.09+/-38017.46 vs 14059.91+/-9030.96, p=0.016) scores, PSQI(10.10+/-4.95 vs 6.90+/-3.81, p=0.002), MDS-UPDRS-I(18.60+/-6.75 vs 12.20+/-3.68, p=0.011), MDS-UPDRS-II(17.30+/-7.29 vs 11.90+/-8.67, p=0.002), and MDS-UPDRS-IV(7.50+/-3.75 vs 3.40+/-2.95, p=0.003). Conclusion: In this unblinded, feasibility study, cueing with the CUE1 appeared to be a feasible and safe intervention for PwP improving motor and non-motor features.

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Vibro-Tactile Stimulation as a Non-Invasive Neuromodulation Therapy for Cervical Dystonia: A Case Study

Cited by 2 publications

References 29 publications

Research progress in spasmodic torticollis rehabilitation treatment

Research progress in spasmodic torticollis rehabilitation treatment

A Pilot Interventional Study on Feasibility and Effectiveness of the CUE1 device in Parkinson’s disease

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