Vicryl Hypersensitivity Test With Histological Response

Stocco, Chiara; Berton, Federico; Papa, Giovanni; Bussani, Rossana; Arnež, Zoran Marij

doi:10.1097/der.0000000000000182

Cited by 18 publications

(15 citation statements)

References 4 publications

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“…the 4 months prior or after the ovariectomy. In anticipation of a potential complication, some medical doctors now use patch testing based using a published visual [3] or histologic [9] grading system to evaluate sensitivity prior to use of Vicryl® in their patients prior to elective cosmetic procedures. However, the feasibility of this in a veterinary or laboratory animal setting is questionable.…”

Section: Discussionmentioning

confidence: 99%

“…Three-layer closure of the incision was accomplished using PDS II® (polydioxanone) 6 in a simple continuous pattern (size 2 for linea alba, size 0 for subcutaneous tissue, and size 2 − 0 for intradermal). Pre-operative analgesia was provided with Buprenorphine SR 7 (0.2 mg/kg SQ once), meloxicam 8 (0.4 mg/kg, SQ, once), and a local incisional block (5 mL 2% Lidocaine 9 ). Post-operatively carprofen 10 (4 mg/kg, PO, q24) was provided for 3 days.…”

Section: Case Presentationmentioning

confidence: 99%

“…All abscesses were sterilely lanced and flushed with dilute betadine and sterile saline and allowed to heal open. Aerobic, anaerobic, and fungal cultures were submitted to an external laboratory 9 , but all yielded no growth. Cytology taken at time of debridement was unchanged and characterized by neutrophilic inflammation.…”

Section: Case Presentationmentioning

confidence: 99%

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Significantly delayed polyglactin 910 suture-related pseudoinfection in a Yucatan pig

Collins

Simons

2020

BMC Vet Res

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Background Polyglactin 910 is a synthetic braided, absorbable suture commonly used in surgery. Though polyglactin 910 suture-related pseudoinfection is well documented in the human literature, it has not been previously reported in the veterinary literature. Case description A 3-year-old female, ovariectomized but otherwise experimentally naïve Yucatan pig was evaluated for a several week history of bilateral multifocal abscesses in the area of the paralumbar fossa, which continued to worsen despite oral antibiotics and non-steroidal anti-inflammatory medications. The multi-focal abscesses continued to worsen and additional diagnostics were pursued including cytology, culture (aerobic, anaerobic and fungal), and bloodwork. All supported a non-infectious etiology. Biopsy results indicated a suture-related pseudoinfection. Despite treatment including parenteral antibiotics, pain medications and superficial surgical debridement, the dermatologic lesions worsened. Euthanasia was elected. Post-mortem necropsy demonstrated a suture-related pseudoinfection with extrusion of suture material from the ovarian pedicle ligatures through the body wall and skin leading to numerous sterile abscesses in the bilateral paralumbar fossa. Conclusions This is the first published report of a significantly delayed polyglactin 910 suture-related pseudoinfection in a Yucatan pig. While likely an isolated incident, it supports further research into this area. Additionally for critical research studies using Yucatan pigs, pre-surgical assessment with hypersensitivity patch testing may be appropriate.

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Section: Discussionmentioning

confidence: 99%

Section: Case Presentationmentioning

confidence: 99%

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Significantly delayed polyglactin 910 suture-related pseudoinfection in a Yucatan pig

Collins

Simons

2020

BMC Vet Res

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“…4 ). Complications (such as hematoma/wound dehiscence, 15 etc.) were encountered in 11 patients (11.9%) (Table 4 ).…”

Section: Resultsmentioning

confidence: 99%

New Algorithm for Chest-wall Surgery and Quality of Life Assessment in Female-to-male Reassignment Patients

Ramella

Papa

Stocco

et al. 2020

Plastic and Reconstructive Surgery - Global Open

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Background: Chest-wall contouring surgery (chest-wall reconstructive surgery) is often the first surgical procedure in female-to-male (FtM) gender reassignment surgery (GRS). The main goal of this procedure is to create an aesthetically pleasing male-like chest contour. No universally accepted algorithm exists for detection of the appropriate surgical technique. Also, there is no tool for objective evaluation of the quality of life and satisfaction of these patients after the operation. Methods: This study involves a single-center clinical trial assessing the patients who underwent subcutaneous mastectomy in FtM GRS between 2003 and 2019. The selection of patients was based on the new “simplified” algorithm consisting of 2 different surgical techniques: the semicircular and the double-incision with free nipple grafting. The selection was based on 3 criteria: breasts size, breast ptosis, and skin elasticity. The outcomes and complication rates were collected and analyzed. The patients’ satisfaction and Quality of Life was assessed with a 5-point Likert scale questionnaire, specifically conceived for FtM patients. The aesthetic evaluation was performed using a 5-point Likert scale dealing with the 5 items featuring as the main goals of GRS. Results: 184 mastectomies were performed in 92 FtM GRS patients. The overall reoperation rate was 11.9%. The patient survey revealed both a high satisfaction rate and a good aesthetic result (4.4/5). Conclusions: The proposed algorithm facilitates the selection of the most suitable technique for top surgery. The patient satisfaction rate evaluated by the proposed Health-Related Quality of Life questionnaire confirmed the outcomes of the use of the algorithm. Further studies to validate the proposed evaluating tools are needed.

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“…A paramedian forehead flap was harvested and mobilized to cover the MFCFF and the forehead donor site closed by suture (Stocco, Berton, Papa, Bussani, & Arnež, ) or secondary healing and a soft dressing with a gentle internal nasal packing was applied. Standard postoperative monitoring was performed on ward (Arnež et al, ).…”

Section: Methodsmentioning

confidence: 99%

Medial femoral condyle free flap in combination with paramedian forehead flap for total/subtotal nasal reconstruction: Level of evidence: IV (therapeutic studies)

et al. 2019

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Background The nose is a functionally complex organ with also a critical role in aesthetics. For reconstruction of full thickness nasal defects, multiple stages are needed and there is risk for resorption resulting in residual deformity. The aim of this report was to develop and evaluate a new method for full thickness total/subtotal nose reconstruction using the medial femoral condyle free flap (MFCFF) in combination with a paramedian forehead flap. Methods Between November 2015 and January 2018, eight patients (four males, four females) mean age 52 years (range 40–73 years) undergoing a total/subtotal nasal excision and subsequential reconstruction with MFCFF plus paramedian forehead flap were enrolled. Six cases were squamous cell carcinomas while two were basal cell carcinomas. The MFCFF was stabilized, with the periosteum as inner layer, with plates and a paramedian forehead flap was used as external skin coverage. All patients were evaluated for with postoperative nasal endoscopy and CT scan. A postoperative questionnaire was given 6 months after surgery. Results The mean MFCFF size was 2–3.8 cm × 2.25–2.5 cm with a mean pedicle length of 6.3 cm (range 4.1–9.4 cm). The postoperative period was uneventful. The mean follow‐up was 16 months, no bone displacement or resorption was observed at the CT scan, no evidence of nasal stenosis occurred. All patients had a satisfying aesthetic evaluation and a good subjective nasal function. Conclusions In this series, the MFCFF in combination with the paramedian forehead flap appeared to provide a valid subtotal nose reconstruction, allowing for the recreation of all the three nasal layers and maintaining the nose projection and airway patency in the long term.

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Vicryl Hypersensitivity Test With Histological Response

Abstract: Vicryl hypersensitivity is rare but its incidence increases. We report the first clinical case diagnosed by a novel testing method implemented by traditional histological analysis

Cited by 18 publications

References 4 publications

Significantly delayed polyglactin 910 suture-related pseudoinfection in a Yucatan pig

Significantly delayed polyglactin 910 suture-related pseudoinfection in a Yucatan pig

New Algorithm for Chest-wall Surgery and Quality of Life Assessment in Female-to-male Reassignment Patients

Medial femoral condyle free flap in combination with paramedian forehead flap for total/subtotal nasal reconstruction: Level of evidence: IV (therapeutic studies)

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