“…Ten interventions were identified. These were anal fistula plug (AFP) ( n = 8) [ 15 , 22 – 24 , 33 , 34 , 36 , 46 ], fibrin glue ( n = 6) [ 17 , 25 , 35 , 40 – 42 ], advancement flap ( n = 4) [ 26 , 32 , 39 , 43 ], fistulotomy ( n = 3) [ 28 , 37 , 38 ], over-the-scope clip (OTSC) ( n = 3) [ 29 , 31 , 44 ], video-assisted anal fistula treatment (VAAFT) ( n = 2) [ 18 , 21 ], adipose-derived stem cells (ASCs) ( n = 3) [ 16 , 45 , 47 ], ligation of intersphincteric fistula track (LIFT) ( n = 2) [ 20 , 27 ], fistula tract laser closure (FiLAC) ( n = 1) [ 19 ], and cone-like resection (CLR) ( n = 1) [ 30 ]. Three studies included more than one intervention [ 34 , 37 , 39 ] (Table 2 ).…”