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Abstract

In summary, it is our opinion that dermatological diseases are highly patterned because the molecular make-up of skin is also highly patterned: pattern reflects function, function reflects morphology, morphology reflects molecular structure and disease reflects molecular perturbationcaused by manifold and sundry aetiologies. By understanding molecular structure, molecular networks, molecular properties and the control of molecular expression, we will understand the disease and its therapies. What generates cutaneous patterning and controls it? Ah, but that is the question…! (e.g. 8-13).