GIS are an essential element in archaeology. Their use has become widespread for their potential to store, reference, analyse and visualise spatial information. Nonetheless, to the best of our knowledge, a systematic review of academic peer-reviewed publications related to the use of GIS, as a framework, in archaeology has never been presented before. Our goal in this work is to identify what has been published so far in relation to using GIS in archaeology within a small selected sample. We used the PRISMA guideline to perform a systematic review of 671 publications that we identified using the SCOPUS database and the keywords ‘GIS’ and ‘archaeology’. The collected publications were screened, analysed, and categorized into different relevant categories. Our analysis shows that GIS, in our selected sample, are mostly used for visualization and information management tasks. Moreover, spatial analysis studies were more common than other studies, and theoretical publications are scarce. The lack of a theoretical background in GIS may be the cause of some of the problems related to GIS applications in archaeology.