VIH et noma au Burkina Faso

Millogo, Mathieu; Konsem, Tarcissus; Ouédraogo, Dieu-Donné; Ouoba, K; Zwetyenga, N.

doi:10.1016/j.stomax.2012.07.004

Cited by 13 publications

(23 citation statements)

References 5 publications

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“…Three articles were not included because the full text data is not available [19,20,21], and eight articles were excluded because patients have the diagnosis of necrotizing ulcerative gingivitis and not noma. Finally, 24 publications that reported 133 cases of noma or noma-like disease in HIV/AIDS patients in the last 22 years, from 1994 to 2016, were selected and included for this review [10][11][12][13][15][16][17][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38] (Table 1).…”

Section: Resultsmentioning

confidence: 99%

“…Although worldwide it appears that HIV infection is not the principal risk factor for noma, the rising trend of noma-like disease in patients with HIV/AIDS appears to mirror the rise in the HIV pandemic, and at least in some countries may play a substantial role in its pathogenesis; to date, its possible relevance has not been fully investigated [8,13,16,17,29,36,37,41].…”

Section: Discussionmentioning

confidence: 99%

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Noma and Noma-like disease in HIV/AIDS patients, a comorbid interaction: A systematic review

Calleros

Castillo-Ventura

Jiménez-Escobar

et al. 2018

J Infect Dev Ctries

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Introduction: Noma is an opportunistic polymicrobial infection that cause necrosis of the mouth and face, with high morbidity and mortality, predominantly affecting malnourished children and persons with debilitating diseases. Cases of noma-like disease in adults, although rare, have been increasingly reported in HIV/AIDS patients particularly in developing countries but also in more developed countries. Methodology: A systematic review of the literature to assess the occurrence and clinical impact of noma and noma-like disease in HIV/AIDS patients was performed on PubMed, Virtual Health Library, Cochrane Library and Google Scholar using the keywords "HIV"[ All Fields] AND "Noma"[All Fields] in December 2016 (years includead for the search: 1985 to 2016). Results: Twenty-four published studies were identified that document the occurrence of noma or noma-like disease in a total of 133 HIV/AIDS children and adult patients in the last 22 years. Although HIV infection is not the principal risk factor for noma, in some regions may play a substantial role in its pathogenesis. The mortality rate for noma-like disease in HIV/AIDS patients was 54.3%, compared to the 15% mortality rate of treated noma patients without HIV/AIDS. Most of the cases have never been on antiretroviral therapy, and their HIV infection was discovered because of the noma-like disease. Conclusions: The syndemic interaction between HIV/AIDS and noma-like disease adversely impacts the severity of the disease and the mortality rate. Noma-like disease, although not yet considered a specific or frequent disease associated with HIV infection, should be considered as an opportunistic infection for AIDS.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Noma and Noma-like disease in HIV/AIDS patients, a comorbid interaction: A systematic review

Calleros

Castillo-Ventura

Jiménez-Escobar

et al. 2018

J Infect Dev Ctries

View full text Add to dashboard Cite

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“…Immunosuppression and infection can be considered predominant factors in noma occurrence, and this correlation is supported by European, Asian, and African studies [10,11,[19][20][21].…”

Section: Discussionmentioning

confidence: 65%

“…However, such a wound can be a gateway for the microorganisms that cause noma [2]. Immunosuppression, induced in our case by CLL, can therefore be described as a contributing factor for noma occurrence [2,10,11]. -Late CLL diagnosis.…”

Section: Discussionmentioning

confidence: 85%

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Chronic lymphocytic leukemia revealed by a rare complication: Noma. First description from Togo

Bouassalo¹,

Mossi

Padaro

et al. 2019

J Oral Med Oral Surg

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Introduction: Noma is defined as a gangrenous ulcerative stomatitis whose starting point is endobuccal. Its exact etiology remains unknown, but many risk factors have been described (malnutrition, poor hygiene, etc.). Chronic lymphoid leukemia (LLC) is a lymphoproliferative syndrome characterized by medullary proliferation of a B lymphocyte clone. It is not considered as a risk factor for noma disease. Observation: A 43-year-old patient is admitted in the odontostomatology unit of the Dapaong Regional Hospital Centre (Togo) for a deep lesion of the left cheek. The clinical examination allows to conclude the presence of a noma. Biological examinations also show a LLC at Binet stage C. In our patient, the LLC is associated with an immunosuppression and the development of infections due to the late diagnosis of the LLC. Comment: The immunosuppression and the development of infections are described in the literature as risk factors for noma disease. An association between LLC and noma could therefore exist. However, such association has been reported to date only once in the literature in 1976. Conclusion: Our observation suggests that the LLC could be a risk factor for noma disease. However, further studies based on large samples are necessary to conclude a causal association between LLC and noma.

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Cancrum oris and hemiparesis in a young female patient—a case report

Ngokwe,

Gimel,

Ntep David Bienvenue

et al. 2024

Clinical Case Reports

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Key Clinical MessageNoma is still around today and can be deadly if ignored. Prompt identification and comprehensive care are essential for averting permanent impairments and disfigurements.AbstractNoma is a rapid developing orofacial gangrene and a disabling disease that primarily affects young children who live in dangerous conditions. Underlying diseases such as HIV/AIDS and malnutrition can enhance the likelihood of Noma's emergence. This is a case of a 9‐year‐old girl patient who arrived malnourished and with an ulcerating communicating right mandibular soft tissue lesion as well as right hemiparesis which had an acute onset. The patient was likewise HIV positive discovered upon admission, possibly as a result of vertical transmission, and was an ART (antiretroviral therapy) treatment naive patient. A holistic treatment plan was installed and a positive clinical response was observed. Early treatment is key in Noma management.

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VIH et noma au Burkina Faso

Cited by 13 publications

References 5 publications

Noma and Noma-like disease in HIV/AIDS patients, a comorbid interaction: A systematic review

Noma and Noma-like disease in HIV/AIDS patients, a comorbid interaction: A systematic review

Chronic lymphocytic leukemia revealed by a rare complication: Noma. First description from Togo

Cancrum oris and hemiparesis in a young female patient—a case report

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