Vinpocetine and coenzyme Q10 combination alleviates cognitive impairment caused by ionizing radiation by improving mitophagy

Hu, Fan; Nie, Huan; Xu, Renxu; Cai, Xin; Shao, Lei; Zhang, Ping

doi:10.1016/j.brainres.2022.148032

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Studies On the Pharmacological Effects Of Vinpocetine1

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2024

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“… 36 Hu demonstrated that the combination of Vinpocetine and coenzyme CoQ10 ameliorated neuronal damage, promoted mitochondrial phagocytosis, and alleviated cognitive deficits in ischemia-reperfusion (IR) mice. 37 Park 38 found that both vincristine and ferulic acid improved memory function by reducing amyloid β-protein tangles in the hippocampus by enhancing insulin action induced in Alzheimer's disease in type 2 diabetic rats. It is further suggested that the combination of the two may improve the efficacy against memory impairment, but related studies have not yet been conducted.…”

Section: Studies On the Pharmacological Effects Of Vinpocetinementioning

confidence: 99%