Karbala provides theoretical assistance for lead pollution prevention by determining blood levels and identifying relevant risk factors among adolescents. Blood lead levels determine by Graphite Furnace Atomic Absorb piton Spectrometry (GFAAS) result. Methods blood samples were taken from both males and females. A total of 100 subjects (average age of 13-17 years, 8 females, and 92 males) were included. The arithmetic means, sample characteristics between two levels of lead concentrations (Less than 100µg/L lead concentration and more or equal 100µg/L lead concentration were patients their number 50 and control also 50 Mean ± SE 49.36 ± 6.61 patients mean ± SE 184.18 ± 6.61 control. Education, His relationship with his parents, Living, Smoking. (T= 7.79**, 4.39**, 4.30**, 4.87**, resp.), while Samples Patients and control (T=18.86**).Conclusions. The levels of lead in the blood of adolescents 13 to 17 years in Karbala governorate were higher than in other areas due to leaving schools and working in different professions at an early age and living in unhealthy families.