Vipera palaestinae envenomation-induced bradycardia

Blum, Arnon; Tatur, Imad; Simsolo, Claudia

doi:10.1016/j.ejim.2004.01.009

Cited by 5 publications

(7 citation statements)

References 2 publications

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“…54 Cardiac arrhythmias have been reported in both people and dogs after V. palaestinae envenomation, although a specific cardiotoxin has yet to be demonstrated in this viper's venom. [55][56][57] Cardiac troponins (cTn) are responsible for regulating myocardial calcium-mediated actin-myosin interactions. In people and dogs, cTn-I and cTn-T have similar structures and are sensitive and specific biomarkers of myocardial injury.…”

Section: Biochemical Changesmentioning

confidence: 99%

Clinicopathologic abnormalities associated with snake envenomation in domestic animals

Goddard¹,

Schoeman²,

Leisewitz³

et al. 2011

Veterinary Clinical Pathol

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Envenomation of domestic animals by snakes occurs frequently in certain geographic areas.However, reports describing clinical signs, clinicopathologic abnormalities, therapeutic approaches, and outcomes are sparse. This review summarizes various snake families, venom types associated with harmful snakes, and the significant hematologic, hemostatic, and biochemical abnormalities associated with envenomation. Hematologic abnormalities include RBC membrane abnormalities, hemolysis, hemoconcentration, leukogram changes, and platelet abnormalities, specifically thrombocytopenia.Coagulopathies associated with snake envenomation are well described in human medicine, and many studies have demonstrated properties of venoms that lead to both procoagulation and anticoagulation.As expected, similar abnormalities have been described in domestic animals. Biochemical abnormalities are associated with the effects of venom on tissues such as liver, skeletal and cardiac 2 muscle, vascular endothelium, and kidney as well as effects on protein components and cholesterol.This comprehensive review of clinicopathologic abnormalities associated with envenomation and their relationship to characterized venom constituents should be useful both in the diagnosis and management of envenomation and serve as a foundation for future research in this field.

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Section: Biochemical Changesmentioning

confidence: 99%

Clinicopathologic abnormalities associated with snake envenomation in domestic animals

Goddard¹,

Schoeman²,

Leisewitz³

et al. 2011

Veterinary Clinical Pathol

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show abstract

“…Cardiac arrhythmias have been reported previously after V. palaestinae envenomation in both canine and human patients 6,8 . In a retrospective study, 2/16 dogs fatally envenomed by V. palaestinae presented with cardiac arrhythmias that were judged severe enough to justify lidocaine treatment 7 .…”

mentioning

confidence: 90%

“…A 6-lead ECG g was recorded upon admission and at 8,16,24,36,40, and 48 hours postenvenomation (36, 23, 29, 29, 24, 14, and 7 dogs, respectively). Additional lead II rhythm strips were recorded from selected patients that were hospitalized for longer periods at 56, 64, 72, 88, and 96 hours postenvenomation (4, 2, 3, 3, and 3 dogs, respectively).…”

Section: Electrocardiographic Evaluationmentioning

confidence: 99%

“…Cardiac arrhythmias have been reported previously after V. palaestinae envenomation in both canine and human patients. 6,8 In a retrospective study, 2/16 dogs fatally envenomed by V. palaestinae presented with cardiac arrhythmias that were judged severe enough to justify lidocaine treatment. 7 In another recent study of V. palaestinae envenomation in dogs, cardiac arrhythmias were detected in 6 of 16 dogs that were periodically monitored electrocardiographically during hospitalization.…”

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confidence: 99%

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Cardiac Arrhythmias and Serum Cardiac Troponins in Vipera palaestinae Envenomation in Dogs

Segev

Ohad

Shipov

et al. 2008

Veterinary Internal Medicne

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“…Daboia deserti venom is largely undescribed and its medical significance is uncertain. Daboia palaestinae is reported to be the most medically significant species in the regions it can be found [167][168][169]. The venom constituents of this species include haemorrhagic SVMPs, neurotoxic PLA2s, and SVSPs [165,170,171].…”

Section: Introductionmentioning

confidence: 99%

Characterising venom variation and antivenom effectiveness within the “True” vipers (Viperinae: Viperidae)

Brouw¹

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Vipera palaestinae envenomation-induced bradycardia

Cited by 5 publications

References 2 publications

Clinicopathologic abnormalities associated with snake envenomation in domestic animals

Clinicopathologic abnormalities associated with snake envenomation in domestic animals

Cardiac Arrhythmias and Serum Cardiac Troponins in Vipera palaestinae Envenomation in Dogs

Characterising venom variation and antivenom effectiveness within the “True” vipers (Viperinae: Viperidae)

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