Viral and non-viral infections in the etiopathogenesis of uveitis

Кричевская, Г. И.; Катаргина, Л. А.

doi:10.17116/oftalma2020136011124

Cited by 3 publications

(1 citation statement)

References 25 publications

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“…В литературе есть данные о случаях первичного развития увеита после применения вакцин против вируса гриппа, герпеса, кори, паротита, ветряной оспы [8].…”

Section: рис 3 серошкальное в-сканирование шварта тянущаяся от област...unclassified

Multimodal Visualization of Ophthalmic Manifestations of Long-COVID-19. Clinical Case

Юсеф¹,

Анджелова²,

Казарян³

et al. 2023

Офтальмология. Восточная Европа

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В эпоху эпидемии коронавирусной инфекции 2019 г. (COVID-19) и борьбы с вирусом SARS-CoV-2 резко возросло число случаев глазной патологии, в частности воспалительного характера. Причиной тому может быть как сама коронавирусная инфекция, так и активная иммунизация населения вакцинами. Вакцина как триггер способна запускать каскад аутоиммунных реакций с развитием воспалительного ответа. Описано немало побочных явлений вакцинации против SARS-CoV-2. Частым осложнением перенесенной коронавирусной инфекции и вакцинации является воспаление сосудистой оболочки глаза. Значительные и порой необратимые зрительные нарушения вследствие аутоиммунного ответа, обусловленного вакцинацией или коронавирусной инфекцией, требуют высокой осведомленности врачей о возможных офтальмологических проявлениях. В статье описывается случай отдаленных офтальмологических проявлений перенесенной инфекции COVID-19 на фоне предшествующей ей иммунизации вакциной Pfizer/BioNTech (BNT162b2) против данной вирусной инфекции. С помощью высокотехнологичных методов исследования выявлены и описаны изменения заднего отрезка глаза вследствие перенесенного ранее увеита. Клинический случай демонстрирует, что COVID-19 и вакцинация против него, предположительно, могут играть роль в индукции иммунного ответа с развитием воспалительного процесса глаз. In the era of the epidemic of coronavirus infection in 2019 (COVID-19) and the fight against the SARS-CoV-2 virus, the number of cases of ocular pathology, in particular of an inflammatory nature, has sharply increased. The reason for this may be both the coronavirus infection itself and the active immunization of the population with vaccines. The vaccine as a trigger is able to trigger a cascade of autoimmune reactions with the development of an inflammatory response. Many side effects of vaccination against SARS-CoV-2 have been described. A common complication of a coronavirus infection and vaccination is inflammation of the vascular membrane of the eye. Significant and sometimes irreversible visual disturbances due to an autoimmune response caused by vaccination or coronavirus infection require high awareness of doctors about possible ophthalmological manifestations. The article describes a case of distant ophthalmological manifestations of a COVID-19 infection against the background of a previous vaccination Pfizer/BioNTech (BNT162b2) against this viral infection. With the help of high-tech research methods, changes in the posterior segment of the eye due to previously transferred uveitis have been identified and described. A clinical case demonstrates that COVID-19 and vaccination against it, presumably, can play a role in the induction of an immune response with the development of an inflammatory of eye.

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Section: рис 3 серошкальное в-сканирование шварта тянущаяся от област...unclassified

Multimodal Visualization of Ophthalmic Manifestations of Long-COVID-19. Clinical Case

Юсеф¹,

Анджелова²,

Казарян³

et al. 2023

Офтальмология. Восточная Европа

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Evolution of Diagnostic Methods for Infectious and Non-Infectious Uveitis. Review

2022

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Uveitis is an inflammation of the uvea (iris, ciliary body, choroid) that can spread to the retina, vitreous and other structures of the eye. Non-infectious uveitis accounts for 31.5 to 82.9 % of cases. The prevalence of infectious uveitis ranges from 13.0 to 54.7 %. Verification of the etiological diagnosis of uveitis requires an individual approach in each clinical case and is based on a thorough analysis of the patient’s medical history, the presence of systemic diseases, and physical examination data, which is supplemented by various laboratory and instrumental examination. However, despite the widespread development of modern diagnostic capabilities, the etiology of uveitis remains unknown in 30–50 % of cases after non-invasive studies, and the treatment is prescribed empirically. At the present stage of studying this issue, the search for a pathological agent, that can play both an etiological role in the development of infectious uveitis and a trigger role in the non-infectious process, is still an urgent task. The article presents a review of the literature on the evolution of methods for the diagnosis of infectious and non-infectious uveitis in accordance with changing ideas about the etiology and pathogenesis of the disease, epidemiological, geographical and socio-economic factors, improving surgical techniques. Pathogenetic aspects and the role of infections in the development of non-infectious uveitis are discussed.

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Surgical Treatment of Cataracts Complicated by Chronic Uveitis. Literature Review

Safonova,

Shilovskikh,

Kazaikin

2024

Oftalʹmologiâ

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The problem of surgical treatment of cataracts in patients with chronic uveitis is relevant due to a high proportion of intra and postoperative complications, despite the development of modern microinvasive technologies. Associated complications of chronic uveitis (adhesions in the anterior eye segment, secondary glaucoma, vitreous opacities, cystoid macular edema, etc.), difficulties in intraocular lens implantation, the need for pharmacological support and subsequent rehabilitation of patients complicate surgery, while many issues remain controversial. Late patients’ recourse for medical aid, severity and duration of the inflammatory process contribute to irreversible changes in the retina, which results in poor functional results of surgery. The development of surgical technologies minimizing the risk of intra and postoperative complications is relevant today.

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Viral and non-viral infections in the etiopathogenesis of uveitis

Cited by 3 publications

References 25 publications

Multimodal Visualization of Ophthalmic Manifestations of Long-COVID-19. Clinical Case

Multimodal Visualization of Ophthalmic Manifestations of Long-COVID-19. Clinical Case

Evolution of Diagnostic Methods for Infectious and Non-Infectious Uveitis. Review

Surgical Treatment of Cataracts Complicated by Chronic Uveitis. Literature Review

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