2008
DOI: 10.2174/187152308784533159
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Viral Anti-Inflammatory Proteins: The Potential for Immunotherapeutic Applications in Cancer

Abstract: Complex viruses such as herpes, poxvirus, HIV and influenza subvert the immune system, blocking host antiviral defenses. The innate immune inflammatory response represents the first line of defense against invading pathogens. This first line of defense also initiates cellular healing after infection or injury. With tumors, however, the innate immune response is a classic double-edged sword, with the capacity to promote or terminate tumor progression. The proliferation and invasion of many cancers as well as me… Show more

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