1987
DOI: 10.1001/archneur.1987.00520240019006
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Viral Antibody Titers

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Cited by 52 publications
(8 citation statements)
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“…Removing the two studies [18], [35] which measured EBNA complex had no effect on the overall result (OR 4.56, 95% CI 3.27–6.37). Another seven studies [17], [23], [31], [32], [39], [43], [46] did not clearly state which form of EBNA was measured; if these are also removed the result is little changed (OR 4.30, 95% CI 2.90–6.39).…”
Section: Resultsmentioning
confidence: 99%
“…Removing the two studies [18], [35] which measured EBNA complex had no effect on the overall result (OR 4.56, 95% CI 3.27–6.37). Another seven studies [17], [23], [31], [32], [39], [43], [46] did not clearly state which form of EBNA was measured; if these are also removed the result is little changed (OR 4.30, 95% CI 2.90–6.39).…”
Section: Resultsmentioning
confidence: 99%
“…In SLE and MS, titers of antibodies against EBV antigens are elevated compared to healthy controls [13,21,22,23], and for both diseases, this elevation seems to predate the first symptoms [24,25,26,27]. Anti-EBV nuclear antigen (EBNA)-1 IgG titers may also predict conversion from clinically isolated syndrome (CIS) to MS [28] and be a marker of MS disease activity [29], although the latter has been questioned by a recent study [30].…”
Section: Evidence Of Associationmentioning
confidence: 99%
“…For SLE, there is some evidence that titers of IgA antibodies against viral capsid antigen (VCA) may be associated with disease flares [34]. There is also some evidence that patients with RA have elevated serum titers of antibodies against EBV antigens [15,23,35,36,37]. However, in contrast to SLE and MS, it does not seem to be any association between the titers of antibodies and risk of subsequent RA [38].…”
Section: Evidence Of Associationmentioning
confidence: 99%
“…Moreover, RA patients have high numbers of circulating EBV-infected B cells (7) and EBV DNA loads in saliva (8). Antibody titers against EBV antigens are also elevated in SLE and MS patients compared to those in healthy controls (9,10).…”
mentioning
confidence: 99%