Viral conjunctivitis: a retrospective study in an Australian hospital

Marinos, Emmanuel; Cabrera‐Aguas, Maria; Watson, Stephanie

doi:10.1016/j.clae.2019.07.001

Cited by 14 publications

(15 citation statements)

References 21 publications

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“…Clinical differentiation of viral from bacterial infection is particularly difficult, with 'classical' signs and symptoms being poor predictors of infectious cause. 15 Around 90-95% of GPs prescribe antibiotics for conjunctivitis, even for cases they feel to be of viral origin. 8,16 Antibiotics have only modest benefit in bacterial conjunctivitis, with marginal clinical and microbiological improvement associated with their use, 17 particularly in paediatric cases.…”

Section: Introductionmentioning

confidence: 99%

Antibiotic prescribing patterns of general practice registrars for infective conjunctivitis: a cross-sectional analysis

Cherry

Tapley

Quain

et al. 2021

J. Prim. Health Care

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INTRODUCTION: Over-prescription of antibiotics for common infective conditions is an important health issue. Infective conjunctivitis represents one of the most common eye-related complaints in general practice. Despite its self-limiting nature, there is evidence of frequent general practitioner (GP) antibiotic prescribing for this condition, which is inconsistent with evidence-based guidelines. AIM: To investigate the prevalence and associations of GP registrars' (trainees') prescription of antibiotics for infective conjunctivitis. METHODS: We performed a cross-sectional analysis of the Registrar Encounters in Clinical Training (ReCEnT) ongoing prospective cohort study, which documents GP registrars' clinical consultations (involving collection of information from 60 consecutive consultations, at three points during registrar training). The outcome of the analyses was antibiotic prescription for a new diagnosis of conjunctivitis. Patient, registrar, practice and consultation variables were included in uni-and multivariable logistic regression analyses to test associations of these prescriptions. RESULTS: In total, 2333 registrars participated in 18 data collection rounds from 2010 to 2018. There were 1580 new cases of infective conjunctivitis (0.31% of all problems). Antibiotics (mainly topical) were prescribed in 1170 (74%) of these cases. Variables associated with antibiotic prescription included patients' Aboriginal or Torres Strait Islander status, registrar organisation of a follow up (both registrar and other GP follow up), and earlier registrar training term (more junior status). DISCUSSION: GP registrars, like established GPs, prescribe antibiotics for conjunctivitis in excess of guideline recommendations, but prescribing rates are lower in later training. These prescribing patterns have educational, social and economic consequences. Further educational strategies may enhance attenuation of registrars' prescribing during training.

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Section: Introductionmentioning

confidence: 99%

Antibiotic prescribing patterns of general practice registrars for infective conjunctivitis: a cross-sectional analysis

Cherry

Tapley

Quain

et al. 2021

J. Prim. Health Care

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“…EKC is the most frequent reason for patient presentation at the ophthalmic emergency room, globally [ 8 ]. The chief complaints are eyelid swelling, eye redness, watering and itching, while the most prevalent clinical signs are conjunctival hyperemia, follicles and pseudomembranes [ 7 , 8 ].…”

Section: Discussionmentioning

confidence: 99%

Orbital inflammatory disease secondary to epidemic keratoconjunctivitis in an adult patient: case report

Abikoye¹

2021

Pan Afr Med J

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Orbital inflammatory disease, sequel to epidemic keratoconjunctivitis is an uncommon finding in adult patients. A 36-year-old male presented at the clinic with a 4-day history of left ocular pain and a one-month history of left eye redness and watering. Visual acuity in the eye was 6/5, with reduced red-color saturation and light brightness appreciation. Left eye examination showed periorbital fullness, a palpably enlarged and tender lacrimal gland, conjunctival follicles with pseudomembranes, and restriction of extraocular motility. Magnetic resonance imaging showed homogenous enhancement of the left lacrimal gland, lateral rectus muscle, pre and post-septal soft tissues. A diagnosis of left orbital inflammatory disease secondary to epidemic keratoconjunctivitis was made and patient was treated with high dose oral steroids over the course of 7 weeks, with complete resolution of clinical symptoms. In conclusion, orbital inflammatory disease can develop following epidemic keratoconjuctivitis in adults with good clinical response to oral steroids. Clinicians should have a high index of suspicion when assessing adult patients for orbital inflammatory disease.

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“…Another study found that when DNA of AdVs is detected in TLR or in plasmacytoid dendritic cells there was an increase stimulation for the production of interferon alpha (15) One study concluded that viral conjunctivitis affects patients in all age groups regardless of ocular history (16). The researcher suggested that proper hygienic and disinfection of possibly contaminated environmental surfaces should be routinely practiced to minimize the dissemination of HAdV-associated conjunctivitis (13) .…”

Section: Discussionmentioning

confidence: 99%

Genotyping of Human Adenovirus Causing Conjunctivitis and Correlation to Age and Gender in Al-Diwaniyah Province in Iraq

Muntadher A. Hawass,

Wisam S. Alrubaye,

Haider Aswad Layikh

2021

Indian Journal of Forensic Medicine & Toxicology

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Human conjunctival swab samples from 108 patients were male 58 (53.7 %) and female 50 (46.3 %) with a male to female ratio of 1.16:1.for the period from October 2019 to February 2020. Patients were selected according to clinical diagnosis by a specialist ophthalmologist. Diagnosis was confirmed by real time PCR that showed 84 patients (77.8%) with positive result; %).The study groups were divided into groups with different age and gender. Those aged 15-40 years had much likely to be infected than those aged 55 years. Positive rate in mild cases was 8 (26.7 %), in moderate cases was 40(95.2 %) and in severe cases was 36 (100.0 %). Phylogenetic tree analysis of local conjunctivitis based on the Hexon gene partial sequence of human adenovirus show genetic relation to human adenovirus 8 and 56 hexon gene .

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Viral conjunctivitis: a retrospective study in an Australian hospital

Cited by 14 publications

References 21 publications

Antibiotic prescribing patterns of general practice registrars for infective conjunctivitis: a cross-sectional analysis

Antibiotic prescribing patterns of general practice registrars for infective conjunctivitis: a cross-sectional analysis

Orbital inflammatory disease secondary to epidemic keratoconjunctivitis in an adult patient: case report

Genotyping of Human Adenovirus Causing Conjunctivitis and Correlation to Age and Gender in Al-Diwaniyah Province in Iraq

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