Viral Diseases

Cassano, Amy; Rasmussen, Skye; Wolf, Felix R

doi:10.1016/b978-0-12-380920-9.00031-6

Cited by 5 publications

(14 citation statements)

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“…There are 3 main outcomes of HaPyV infection: subclinical effects, tumors of the hair follicle (trichoepitheliomas), and tumors of the hematopoietic system (most often lymphoma). 11 However, the hamster of this report did have multiple tumors in the skin and hematopoietic system, making the case unique. 11 Infection of older hamsters is typically subclinical with continued viruria as a result of persistence of HaPyV in the renal tubular epithelium.…”

Section: Commentsmentioning

confidence: 80%

“…5,11 With natural HaPyV infection in Syrian hamsters, the virus is transmitted horizontally via urine. 11 Infection of older hamsters is typically subclinical with continued viruria as a result of persistence of HaPyV in the renal tubular epithelium. There are 3 main outcomes of HaPyV infection: subclinical effects, tumors of the hair follicle (trichoepitheliomas), and tumors of the hematopoietic system (most often lymphoma).…”

Section: Commentsmentioning

confidence: 99%

“…1,4,5,9 In the case described in the present report, it was assumed that the pet hamster was infected prior to its purchase at 1 month of age because it was housed singly and had no interaction with other hamsters. 5,11 Concurrent formation of epitheliomas and lymphomas in an individual hamster is a rare occurrence. 1,4,5,9 The syndrome that develops depends on the overall immunologic status of the hamster colony and the age of the infected animal.…”

Section: Commentsmentioning

confidence: 99%

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Pathology in Practice

Compton²,

Cj³

2014

javma

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HistoryAn approximately 10-month-old female Syrian hamster (Mesocricetus auratus) was submitted for necropsy. The pet had died following a 6-week period of weight loss, lethargy, and tachypnea with increased abdominal effort. The hamster was previously evaluated by a veterinary ophthalmologist because of several small nodules on both lower eyelids at the medial canthus; on the basis of the physical examination findings, these nodules were diagnosed as cysts.On external examination of the hamster, there were dozens of slightly raised, light pink to pale tan cutaneous nodules (range of diameter, 0.1 to 0.2 cm; Figure 1). The nodules were scattered over the back, ventral aspect of the abdomen, limbs, neck, and chin and were of similar appearance to the masses on the lower eyelids. The thoracic cavity was filled with white, opaque fluid (chylous effusion), and there was a soft, pale tan, multinodular mass (1.5 X 1 X 1 cm) at the base of the heart. The liver was diffusely and markedly enlarged (congestion).

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Section: Commentsmentioning

confidence: 80%

Section: Commentsmentioning

confidence: 99%

Section: Commentsmentioning

confidence: 99%

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Pathology in Practice

Compton²,

Cj³

2014

javma

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“…The hamster is the most common animal species to transmit LCMV to humans (Cassano et al, 2012); however, the laboratory mouse, Mus musculus, is the primary reservoir for the virus.…”

Section: Lymphocytic Choriomeningitis Virusmentioning

confidence: 99%

“…Hamsters from different sources should not be housed in the same room unless all sources are known to be free of the virus. Animal-derived biological products should be screened by PCR or hamster antibody production (HAP) test before use in colony hamsters (Cassano et al, 2012). Dirtybedding sentinels have been shown to be only variably efficacious in detecting SV outbreaks in mice (Compton et al, 2004), therefore, colony surveillance measures may need to be modified.…”

Section: Sendai Virus Etiology Sendai Virus Is a Single-strandedmentioning

confidence: 99%