2024
DOI: 10.1080/20002297.2024.2345941
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Viral DNA in submandibular gland tissue with an inflammatory disorder

Noora Keski-Säntti,
Elin Waltimo,
Antti Mäkitie
et al.

Abstract: Background The etiology behind different types of chronic sialadenitis (CS), some of which exhibit IgG4 overexpression, is unknown. Further, IgG4-related disease (IgG4-RD) commonly affects the submandibular gland, but its relationship to IgG4-overexpressing CS, and the antigen triggering IgG4 overexpression, remain unknown. Materials and Methods By qPCR, we assessed the presence of 21 DNA-viruses causing IgG4 overexpression in submandibular gland tissue from patients wi… Show more

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