Viral inactivation by light

Abstract

Nowadays, viral infections are one of the greatest challenges for medical sciences and human society. While antiviral compounds and chemical inactivation remain inadequate, physical approaches based on irradiation provide new potentials for prevention and treatment of viral infections, without the risk of drug resistance and other unwanted side effects. Light across the electromagnetic spectrum can inactivate the virions using ionizing and non-ionizing radiations. This review highlights the anti-viral utility of radiant methods from the aspects of ionizing radiation, including high energy ultraviolet, gamma ray, X-ray, and neutron, and non-ionizing photo-inactivation, including lasers and blue light.

Improved Near-Infrared Luminescence Properties of LiScSi2O6:Cr3+,Yb3+ Phosphors via Efficient Energy Transfer

“…Near-infrared (NIR) light is widely used in biomedicine, disease detection, food detection, identity verification, and night vision imaging due to its low energy, high penetration, and nondestructive nature. − Traditional NIR light resources such as halogen lamps and supercontinuum lasers are large and exhibit low efficiency, while semiconductor light-emitting diodes (LEDs) are limited by the narrow full width at half-maximum (fwhm, <50 nm). , The wider the wavelength range, the wider the application range of the material. NIR phosphor-converted LEDs (NIR pc-LEDs), combining NIR phosphors and commercial blue chips, have been proven to be an efficient device for achieving smart NIR light devices. − Thereby, the development of efficient and broadband NIR phosphors that can be effectively excited by blue light is the key to achieving high-performance NIR pc-LEDs.…”

Highly resolved and refreshable X-ray imaging from Tb3+doped aluminosilicate oxyfluoride glass scintillators

“…[7][8][9] However, drawbacks such as the costly spend and time-consuming preparation of single crystals motivate the investigation of alternative scintillation materials, e.g., glass, flexible films, inorganic polycrystals, perovskite and so on. 6,[10][11][12][13][14][15][16][17][18][19][20] Glasses are renowned transparent optical functional hosts because of their flexible components, easy preparation, low cost, low toxicity, mass and large scale production. [21][22][23] Compared to single crystals, the industrial procedures for making glass by the melt-quenching method make it possible to elaborate glass scintillators with a favourable homogeneity of activators, and favourable shapes and sizes, such as fibers and large-area scintillating plates.…”

Long-persistent far-UVC light emission in Pr3+-doped Sr2P2O7 phosphor for microbial sterilization

“…[1][2][3][4][5][6][7] By far, in contrast to the extensive research on luminescent materials emitting in the UVA (320-400 nm) and UVB (280-320 nm) spectral regions, the available materials capable of emitting UVC (200-280 nm) light are relatively lacking, even though there are growing demands for applications in microbial inactivation. [8][9][10][11] Currently, the most widely used UVlight sources are mercury lamps, xenon lamps, and excimer lamps, while these gaseous lamps suffer great limitations due to the unfavorable factors of environmental pollution, poor portability, and fragility. 12,13 Thanks to the rapid development of the light-emitting-diode (LED) industry in recent years, high-performance solid-state deep UV LEDs with the advantages of being more portable and durable, energy-efficient, and environmentally friendly, are increasingly considered a promising alternative to conventional gaseous UV-light sources.…”