Virtual 3D microscopy in pathology education

Zwönitzer, Ralf; Hofmann, Harald; Roessner, Albert; Kalinski, Thomas

doi:10.1016/j.humpath.2009.10.012

Cited by 17 publications

(14 citation statements)

References 7 publications

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“…By contrast, the traditional microscopy classroom is costly to set up to maintain, and high-quality cytology glass slides are impossible to duplicate or replace [32]. WSI is sufficient for cytologists to make reliable diagnostic decisions [6, 31, 33, 34]. …”

Section: Applications Of Wsi In Cytology Education and Trainingmentioning

confidence: 99%

Digital Imaging in Cytopathology

Khalbuss

Pantanowitz

Parwani

2011

Pathology Research International

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Rapid advances are occurring in the field of cytopathology, particularly in the field of digital imaging. Today, digital images are used in a variety of settings including education (E-education), as a substitute to multiheaded sessions, multisite conferences, publications, cytopathology web pages, cytology proficiency testing, telecytology, consultation through telecytology, and automated screening of Pap test slides. The accessibility provided by digital imaging in cytopathology can improve the quality and efficiency of cytopathology services, primarily by getting the expert cytopathologist to remotely look at the slide. This improved accessibility saves time and alleviates the need to ship slides, wait for glass slides, or transport pathologists. Whole slide imaging (WSI) is a digital imaging modality that uses computerized technology to scan and convert pathology and cytology glass slides into digital images (digital slides) that can be viewed remotely on a workstation using viewing software. In spite of the many advances, challenges remain such as the expensive initial set-up costs, workflow interruption, length of time to scan whole slides, large storage size for WSI, bandwidth restrictions, undefined legal implications, professional reluctance, and lack of standardization in the imaging process.

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Section: Applications Of Wsi In Cytology Education and Trainingmentioning

confidence: 99%

Digital Imaging in Cytopathology

Khalbuss

Pantanowitz

Parwani

2011

Pathology Research International

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“…[58] WSI image quality has proven to be sufficient for educational purposes. [565960] Virtual slides may be annotated and shared by participants, such as pathology residents before conferences. [55] With digital slide conferences, advantages include improved access to large teaching sets, enhanced annotations, and instant access to linked related clinical data such as radiology images.…”

Section: Educational and Testing Applicationsmentioning

confidence: 99%

Telecytology: Clinical applications, current challenges, and future benefits

Thrall

Pantanowitz

Khalbuss

2011

Journal of Pathology Informatics

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Telecytology is the interpretation of cytology material at a distance using digital images. For more than a decade, pioneering efforts to introduce telecytology into clinical practice have been reported. A Medline search for “telecytology” and “cytology” reveals a voluminous literature, though much of what has been published to date is based on technologies that are rapidly becoming obsolete. The technological limitations of previous techniques, including the transmission of static digital images and dynamic streaming images, have limited telecytology to minor niches. The primary problem with these technologies is that the remote viewer can only see a small fraction of the material on the original slides, introducing the possibility of diagnostic error based not only on image quality but also on image selection. Remote robotic microscopy offers one possible solution to this problem, but to date has found limited acceptance, principally attributable to slow operating times. Whole slide imaging seems to be a much more promising solution, though cytology-specific literature regarding its use is still scant. The advent of whole slide imaging opens up new possibilities for telecytology by enabling high-quality images of entire cytology specimens to be available to anyone, anywhere via the Internet. Although challenges remain, especially with regard to capturing the full microscopy experience including multiple planes of focus and sharp high-powered images, rapidly advancing technology promises to overcome these limitations. Increasing application of whole slide imaging technology in surgical pathology will undoubtedly also increase its application to cytology due to the increasing affordability and practicality of the equipment as it serves a larger number of useful roles within a pathology department. The current and expanding applications of telecytology for clinical practice, education, quality assurance, and testing will be reviewed.

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“…B. Zoomify (www.zoomify.com) wird das nichtproprietäre JPEG2000-Format verwendet. Die Vorteile von JPEG2000 gegenüber JPEG sind bereits in vorangegangenen Publikationen beschrieben worden [6][7][8][9][10][11]. Tuominen u. Isola [8] haben die höhere Leistungsfähigkeit eines JPEG2000-Servers im direkten Vergleich zu einem JPEG-basierten System (Zoomify) nachgewiesen.…”

Section: Diskussionunclassified

Pathowiki

Roßner

Zwönitzer³

et al. 2012

Pathologe

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The project Pathowiki (www.pathowiki.org) is a free expert database for texts, images, virtual slides and links to all subject areas of pathology in the internet. The aim of this project is to integrate all available information and media, in particular virtual microscopy, to achieve a fast overview of a relevant subject area. Here we present the project’s basic functions and applications and evaluate the project with respect to the ongoing digital developments in pathology.

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Virtual 3D microscopy in pathology education

Cited by 17 publications

References 7 publications

Digital Imaging in Cytopathology

Digital Imaging in Cytopathology

Telecytology: Clinical applications, current challenges, and future benefits

Pathowiki

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