Efforts to mitigate environmental threats are often inversely related to the magnitude of casualty, human or otherwise1–3. This “compassion fade” can be explained, in part, by differential processing of large- versus small-scale threats: it is difficult to form empathic connections with unfamiliar masses versus singular victims4. Despite robust findings, little is known about how non-human casualty is processed, and what strategies override this bias. Over four experiments, we show how embodying threatened megafauna – Loggerhead sea turtles (Caretta Caretta) – in virtual reality can offset and reverse compassion fade. After observing compassion fade during exposure to mass non-human casualty in virtual reality (Study 1; N=60), we then tested a custom multi-sensory virtual reality simulation facilitating embodiment of a threatened Loggerhead (Study 2; N=98). Afterwards, a field experiment (Study 3; N=90) testing the simulation with varied number of victims showed embodiment offset compassion fade. Lastly, a fourth study (N=25) found that charitable giving among users embodying threatened wildlife was highest when exposed to one versus many victims, though this effect was reversed if victims were of a different species (Dolphins). The findings demonstrate how animal embodiment in virtual reality alters processing of environmental threats and non-human casualty, thereby influencing biodiversity conservation outcomes.