Virucidal Effects of Bleach Activators, Sodium Alkyl Acyloxybenzene Sulfonate and Acyloxybenzoic Acid, Against Feline calicivirus

Tobe, Seiichi; Hoshi, Marika; Iizuka, Kinue; Tadenuma, Hirohiko; Takaoka, Hiromitsu; Komoriya, Tomoe; Kohno, Hirotada

doi:10.5650/jos.61.211

Cited by 1 publication

(1 citation statement)

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“…On the other hand, in order to have a basic solution, the sodium carbonate–hydrogen peroxide adduct was chosen as a starting material, since it is a cheap and stable product that contains, at the same time, the active peroxide ingredient and the alkaline modifier. Its use as a biocidal or virucidal agent has been scarcely studied, − and only three products listed in US EPA’s List N contain Na 2 CO 3 ·1.5H 2 O 2 as an active ingredient . Sodium percarbonate can be considered a more robust alternative to diluted hydrogen peroxide, as it can be stored for longer times and transported more easily without any significant loss in active ingredient.…”

Section: Resultsmentioning

confidence: 99%

Inactivation of SARS-CoV-2 in the Liquid Phase: Are Aqueous Hydrogen Peroxide and Sodium Percarbonate Efficient Decontamination Agents?

Mileto

Mancon

Staurenghi

et al. 2021

ACS Chem. Health Saf.

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A diluted 3% w/w hydrogen peroxide solution acidified to pH 2.5 by adding citric acid inactivated SARS-CoV-2 virus by more than 4 orders of magnitude in 5 min. After a contact time of 15 min, no viral replication was detected. Aqueous solutions of sodium percarbonate inactivated coronavirus by >3 log 10 diminution in 15 min. Conversely, H 2 O 2 solutions with no additives displayed a scarce virucidal activity (1.1 log 10 diminution in 5 min), confirming that a pH-modifying ingredient is necessary to have a H 2 O 2 -based disinfectant active against the novel coronavirus.

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Section: Resultsmentioning

confidence: 99%