Virucidal gargling and virucidal nasal spray

Krämer, Axel; Eggers, Maren; Hübner, Nils–Olaf; Walger, Peter; Steinmann, Eike; Exner, Martin

doi:10.3205/dgkh000373

Cited by 9 publications

(10 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To control the global SARS-CoV-2 pandemic, measures such as personal protective equipment (PPE), disinfection, virucidal gargling and nasal spray [ 1 ], window ventilation or mechanical ventilation systems, public restrictions such as business closures, contact and visitor restrictions, vaccination etc. are being used.…”

Section: Introductionmentioning

confidence: 99%

The role of routine SARS-CoV-2 screening of healthcare-workers in acute care hospitals in 2020: a systematic review and meta-analysis

et al. 2022

View full text Add to dashboard Cite

Background Healthcare workers (HCW) are at increased risk of infection with SARS-CoV-2. Vulnerable patient populations in particular must be protected, and clinics should not become transmission hotspots to avoid delaying medical treatments independent of COVID. Because asymptomatic transmission has been described, routine screening of asymptomatic HCW would potentially be able to interrupt chains of infection through early detection. Methods A systematic search was conducted in the Cochrane COVID-19 Study Register, Web of Science and WHO COVID‐19 Global literature on coronavirus with regard to non-incident related testing of healthcare workers using polymerase chain reaction on May 4th 2021. Studies since January 2020 were included. An assessment of risk of bias and representativeness was performed. Results The search identified 39 studies with heterogeneous designs. Data collection of the included studies took place from January to August 2020. The studies were conducted worldwide and the sample size of the included HCW ranged from 70 to 9449 participants. In total, 1000 of 51,700 (1.9%) asymptomatic HCW were tested positive for SARS-CoV-2 using PCR testing. The proportion of positive test results ranged between 0 and 14.3%. No study reported on HCW-screening related reductions in infected person-days. Discussion and conclusions The heterogeneous proportions might be explained by different regional incidences, lock-downs, and pre-analytical pitfalls that reduce the sensitivity of the nasopharyngeal swab. The very high prevalence in some studies indicates that screening HCW for SARS-CoV-2 may be important particularly in geographical regions and pandemic periods with a high-incidence. With low numbers and an increasing rate of vaccinated HCW, a strict cost–benefit consideration must be made, especially in times of low incidences. Since we found no studies that reported on HCW-screening related reductions in infected person-days, re-evaluation should be done when these are available.

show abstract

Section: Introductionmentioning

confidence: 99%

The role of routine SARS-CoV-2 screening of healthcare-workers in acute care hospitals in 2020: a systematic review and meta-analysis

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Prevention approaches can also intervene at early stages of infection by targeting the nose and the mouth as entry points for viruses. 20 These approaches include using mouthwashes and rinses and nasal sprays, douches and irrigation. Products may be used regularly and/or in responsible to possible/probable exposure.…”

Section: Introductionmentioning

confidence: 99%

“… 20 21 The COVID-19 pandemic has prompted a resurgence of interest in these approaches. 20 22–27 Many formulations and products are under investigation, with some promising findings. For example, a systematic review concluded that iota-carrageenan nasal sprays have a good safety profile and powerful antiviral activity against the common cold.…”

Section: Introductionmentioning

confidence: 99%

“…Typical RTI prevention approaches reduce the likelihood of becoming infected (eg, social distancing,11 face coverings11 and handwashing11 12) or improve individuals’ immune responses (eg, vaccination,13–15 nutrition,16 17 physical activity18 19). Prevention approaches can also intervene at early stages of infection by targeting the nose and the mouth as entry points for viruses 20. These approaches include using mouthwashes and rinses and nasal sprays, douches and irrigation.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Using nasal sprays to prevent respiratory tract infections: a qualitative study of online consumer reviews and primary care patient interviews

et al. 2022

View full text Add to dashboard Cite

ObjectivesNasal sprays could be a promising approach to preventing respiratory tract infections (RTIs). This study explored lay people’s perceptions and experiences of using nasal sprays to prevent RTIs to identify barriers and facilitators to their adoption and continued use.DesignQualitative research. Study 1 thematically analysed online consumer reviews of an RTI prevention nasal spray. Study 2 interviewed patients about their reactions to and experiences of a digital intervention that promotes and supports nasal spray use for RTI prevention (reactively: at ‘first signs’ of infection and preventatively: following possible/probable exposure to infection). Interview transcripts were analysed using thematic analysis.SettingPrimary care, UK.Participants407 online customer reviews. 13 purposively recruited primary care patients who had experienced recurrent infections and/or had risk factors for severe infections.ResultsBoth studies identified various factors that might influence nasal spray use including: high motivation to avoid RTIs, particularly during the COVID-19 pandemic; fatalistic views about RTIs; beliefs about alternative prevention methods; the importance of personal recommendation; perceived complexity and familiarity of nasal sprays; personal experiences of spray success or failure; tolerable and off-putting side effects; concerns about medicines; and the nose as unpleasant and unhygienic.ConclusionsPeople who suffer disruptive, frequent or severe RTIs or who are vulnerable to RTIs are interested in using a nasal spray for prevention. They also have doubts and concerns and may encounter problems. Some of these may be reduced or eliminated by providing nasal spray users with information and advice that addresses these concerns or helps people overcome difficulties.

show abstract

“…A wide range of medical and behavioural RTI prevention approaches have been investigated including; hand hygiene,10–12 vaccination,13–15 social distancing,10 16 mask-wearing,10 11 17 vitamins and supplements,18 19 gargling, nasal rinses and nasal sprays,20 exercise21 22 and mindfulness meditation 21. Interest and urgency around RTI prevention has been prompted by the COVID-19 pandemic.…”

Section: Introductionmentioning

confidence: 99%

Patient perceptions of vulnerability to recurrent respiratory tract infections and prevention strategies: a qualitative study

et al. 2022

View full text Add to dashboard Cite

ObjectivesRespiratory tract infections (RTIs) are extremely common, usually self-limiting, but responsible for considerable work sickness absence, reduced quality of life, inappropriate antibiotic prescribing and healthcare costs. Patients who experience recurrent RTIs and those with certain comorbid conditions have higher personal impact and healthcare costs and may be more likely to suffer disease exacerbations, hospitalisation and death. We explored how these patients experience and perceive their RTIs to understand how best to engage them in prevention behaviours.DesignA qualitative interview study.SettingPrimary care, UK.Methods23 participants who reported recurrent RTIs and/or had relevant comorbid health conditions were interviewed about their experiences of RTIs. Interviews took place as the COVID-19 pandemic began. Data were analysed using inductive thematic analysis.ResultsThree themes were developed: Understanding causes and vulnerability, Attempting to prevent RTIs, Uncertainty and ambivalence about prevention, along with an overarching theme; Changing experiences because of COVID-19. Participants’ understandings of their susceptibility to RTIs were multifactorial and included both transmission via others and personal vulnerabilities. They engaged in various approaches to try to prevent infections or alter their progression yet perceived they had limited personal control. The COVID-19 pandemic had improved their understanding of transmission, heightened their concern and motivation to avoid RTIs and extended their repertoire of protective behaviours.ConclusionsPatients who experience frequent or severe RTIs are likely to welcome and benefit from advice and support regarding RTI prevention. To engage people effectively, those developing interventions or delivering health services must consider their beliefs and concerns about susceptibility and prevention.

show abstract

Virucidal gargling and virucidal nasal spray

Cited by 9 publications

References 21 publications

The role of routine SARS-CoV-2 screening of healthcare-workers in acute care hospitals in 2020: a systematic review and meta-analysis

The role of routine SARS-CoV-2 screening of healthcare-workers in acute care hospitals in 2020: a systematic review and meta-analysis

Using nasal sprays to prevent respiratory tract infections: a qualitative study of online consumer reviews and primary care patient interviews

Patient perceptions of vulnerability to recurrent respiratory tract infections and prevention strategies: a qualitative study

Contact Info

Product

Resources

About