Virulence of Babesia bigemina in infected cattle (Bos taurus): Molecular and immunological studies

Attia, Marwa M.; Khalifa, Marwa M.

doi:10.1016/j.rvsc.2023.01.017

Cited by 6 publications

(1 citation statement)

References 26 publications

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“…Parasitic infections pose significant challenges to animal production worldwide, causing substantial economic losses and compromising animal welfare (Jamil et al, 2023). These infections encompass a diverse range of pathogens, including protozoa, helminths, and ectoparasites, that can invade various host species, including livestock, companion animals, and wildlife (Attia and Khalifa, 2023). Among these parasites, ticks stand out as particularly problematic ectoparasites that infest a wide array of animals, including reptiles, amphibians, birds, and mammals (Jamil et al, 2023).…”

Section: Introductionmentioning

confidence: 99%

Assessment of Babesia spp. prevalence in various domestic animals across Southern Punjab, Pakistan

Tariq,

Badshah,

Khan

et al. 2024

Braz. J. Biol.

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Parasitic diseases, notably babesiosis, exert a substantial impact on the global cattle industry, posing challenges to commerce, economies, and human health. This study, conducted in Southern Punjab, Pakistan, aimed to assess the prevalence of Babesia spp. across various livestock species using microscopic and PCR methods. A total of 180 blood samples (60 from each district) were systematically collected from apparently healthy animals, with 36 samples obtained from each domestic animal species, including camel, cattle, buffalo, goat, and sheep, noting that 12 samples were collected from each district for each animal species. Overall prevalence was determined to be 32.8% (59/180), with varying rates among species: 25.0% in cattle, 41.66% in buffalo, 30.55% in goats, 33.3% in sheep, and 33.3% in camels. Microscopic examination revealed slightly varied infection rates among large and small domestic animals (22.2%), while PCR results indicated a 32.8% overall infection rate in both large and small domestic animals, with no statistical significance. District-wise analysis showed regional variations, with Muzaffargarh recording a prevalence rate of 23.33% through microscopic examination, while Lodhran and Bahawalpur recorded 21.67%. PCR results revealed higher rates (38.33%, 26.67%, and 33.33%, respectively), underlining the importance of employing PCR for accurate detection. Examining ruminant types, large ruminants exhibited a 32.4% infection rate, while small domestic animals showed 33.3%, with no significant difference (p=0.897). District-wise prevalence showcased significant variation, with Muzaffargarh demonstrating a 25% prevalence, Lodhran 22%, and Bahawalpur 22%, through microscopic examination. PCR results displayed 38.33%, 27%, and 33.3%, respectively, with no statistical significance. Detailed analysis of individual districts highlighted variations in infection rates among camels, cattle, buffalo, goats, and sheep. The binomial test indicated significant differences through microscopic analysis (P=0.011) but non-significant variations through PCR (P=0.065), emphasizing the precision of PCR. Regional variations in prevalence, notably with Punjab exhibiting the highest frequency (33.87%) and KPK the lowest (13.24%), suggest potential influences from varying veterinary practices and environmental factors. This study underscores the pivotal role of PCR alongside microscopy for accurate babesiosis diagnosis. These findings contribute to the broader understanding of babesiosis prevalence, emphasizing the necessity of advanced molecular techniques for informed control measures.

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Section: Introductionmentioning

confidence: 99%