Virulence of Endodontic Bacterial Pathogens

Sedgley, Christine M.

doi:10.1002/9781119080343.ch7

Cited by 2 publications

(3 citation statements)

References 233 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although specific knowledge about these factors in relation to endodontic bacterial pathogens is limited at present, their importance cannot be overstated. Significant structural differences exist between gram-negative and gram-positive bacteria, particularly in their peripheral structures, as highlighted in (Figure 1) (6). These differences are critical to understanding how bacteria interact with their environment and host.…”

Section: Virulence Factorsmentioning

confidence: 99%

“…It involves not just treating the immediate symptoms but also understanding the underlying causes and interactions between various microorganisms and the body's immune response. This comprehensive approach is vital for the successful treatment of endodontic diseases and for ensuring the longevity and health of the dental and periodontal structures (6). Endodontic therapy, therefore, is not just a dental procedure; it is an integral part of healthcare that requires an interdisciplinary understanding of microbiology, immunology, and pathology.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Pathway of Infections and Virulence Factors in Endodontics

Alsharif,

Rawas,

Zurayn

et al. 2023

JOHS

View full text Add to dashboard Cite

Endodontic treatment has increasingly become a preferred method for tooth preservation, largely due to its consistently high success rates. The success of endodontic therapy, aimed at tooth preservation, has improved due to a deeper understanding of endodontic pathology and advancements in treatment methods. Infections within the root canal, leading to apical periodontitis, are typically polymicrobial with a significant role played by obligate anaerobic bacteria. The study highlights the importance of understanding the intricate pathways of infection, such as through dentinal tubules, open cavities, the periodontal membrane, and the bloodstream, as well as the impact of faulty dental restorations. Key to managing these infections is an in-depth knowledge of the endodontic microbiota and its interplay with various disease states. The review also underscores the role of virulence factors in the pathogenesis of endodontic infections. These factors contribute to bacterial behavior, including adherence, invasion, evasion of host defenses, and induction of proinflammatory cytokines. Understanding these complex interactions is essential for developing effective treatment strategies and enhancing the field of endodontics, with a focus on maintaining long-term oral and overall health.

show abstract

Section: Virulence Factorsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Pathway of Infections and Virulence Factors in Endodontics

Alsharif,

Rawas,

Zurayn

et al. 2023

JOHS

View full text Add to dashboard Cite

show abstract

“…A list of bacterial virulence factors that could contribute to the development of OS through endodontic infection is presented in Table …”

Section: Microbiology Of Odontogenic Sinusitismentioning

confidence: 99%

Pathophysiology of sinusitis of odontogenic origin

Taschieri

Torretta

Corbella

et al. 2015

J of Invest & Clin Dent

View full text Add to dashboard Cite

Sinusitis of odontogenic origin, which is frequently encountered in routine otolaryngological and dental clinical practice, has been described as a reactive maxillary inflammation secondary to maxillary tooth infection or trauma to an odontogenic disease of maxillary bone, dental extractions, implant placement, or endodontic treatment impairing the integrity of the Schneiderian membrane. The aim of the present review was to investigate and discuss the most recent pathophysiological findings, predisposing odontogenic factors, microbiology, and the possible involvement of bacterial biofilms (BB) in the development of sinusitis. The narrative literature review showed that there might be a correlation between the bacteria present in pathological teeth in communication with the sinus and those found in infected sinus. The formation of a BB might be also involved in the etiopathogenesis of sinusitis of odontogenic origin. In conclusion, the true origin of odontogenic sinusitis is still unresolved. In clinical terms, the choice of suitable therapy depends on the characteristics of the biofilm. Further microbiological studies are required to better investigate the role of BB.

show abstract

Virulence of Endodontic Bacterial Pathogens

Cited by 2 publications

References 233 publications

Pathway of Infections and Virulence Factors in Endodontics

Pathway of Infections and Virulence Factors in Endodontics

Pathophysiology of sinusitis of odontogenic origin

Contact Info

Product

Resources

About