Virus de l’hépatite C : étude des génotypes au Congo (Brazzaville)

Atipo-Ibara, B. I.; Mimesse, J.; Bokilo-Dzia, A.; Deby-Gassaye,; Ahoui-Apendi, C.; Bossali, F.; Ngami, Rody Stéphane; Ibara, Jean-Rosaire

doi:10.1007/s12157-014-0506-3

Cited by 3 publications

(3 citation statements)

References 7 publications

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“…The last study conducted among adults in one HIV clinic in the capital, Brazzaville in 2010, showed that the prevalence of HCV antibody was 5.7%. Studies have revealed that the majority of HCV positive patients were predominantly male [ 21 , 51 ].…”

Section: Resultsmentioning

confidence: 99%

“…The data that support the findings of this review are available from [ 19 , 49 ] but restrictions apply to the availability of these data, which were used under license for the current study, and so are not publicly available. Data are however available from the authors upon reasonable request and with permission of Taty-Taty et al ‎(1990) and Atipo-Ibara et al [ 21 , 22 ].…”

Section: Authors’ Contributionsmentioning

confidence: 99%

“…Considered an endemic zone, Congo has a high seroprevalence rate of hepatitis C virus. A study conducted in 2014 among 17,351 blood donors, in the two major cities of the country revealed that the relative frequency was 4.1% in Brazzaville and 4.3% in Pointe-Noire [ 21 ]. At Brazzaville, the seroprevalence rate among 1363 blood donors was documented to be 9.9%.…”

Section: Introductionmentioning

confidence: 99%

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Epidemiology of viral hepatitis in the Republic of Congo: review

Linguissi¹,

Nkenfou

2017

BMC Res Notes

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ObjectiveConsidered an endemic zone, Republic of Congo has a high seroprevalence rate of hepatitis B and C virus. To know the extent of hepatitis infection as a public health problem, we reviewed published literature and other sources for reports of these viral infections in the country.ResultsHigh seroprevalence of HBV and HCV carriage in blood donors were observed in studies confirming Congo’s place in the hyperendemic area of HBV and HCV infection. These prevalence were compared by Chi square test. We compared the prevalence of three studies conducted in 1996, 2015 and 2016. The statistical results were very significant. HBV genotype E was most prevalent. Very few studies were done on pregnant women. Difficulties in the care and management of patients were also noted because of the high cost of often unavailable treatments. Difficulties arise, however, when an attempt was made to implement the National Hepatitis Control Program. Despite studies conducted on hepatitis prevalence, health interventions are still needed to care and manage these patients and the need to implement the national hepatitis control is more pressing in the Congo.

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Section: Resultsmentioning

confidence: 99%

Section: Authors’ Contributionsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Epidemiology of viral hepatitis in the Republic of Congo: review

Linguissi¹,

Nkenfou

2017

BMC Res Notes

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Prevalence of Virological Markers HIV, HBV and HCV in Homozygous Sickle Cell Patients at Brazzaville University Hospital

Kibangou¹,

Moyen²,

Moyen³

et al. 2021

OJBD

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Seroprevalence and Molecular Biodiverisity of Hepatitis C Infection in Congolese Diabetics

Mongo-Onkouo¹,

Ibobi²,

Gassaye³

et al. 2019

OJGas

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It concerned diabetic patients followed in Brazzaville and Pointe-Noire agreeing to the study, after obtaining the opinion of the ethics committee of the research in health science. All samples collected were screened for the presence of anti HCV Ab using a rapid ALERE HCV test and the Monolisa HCV Ag-Ab ultra test for confirmation in Congo. Detection of the viral RNA was done by PCR retrotranscription and genotyping was performed according to the reverse hybridization technique in France. Data analysis was done with EpiInfo 6.0 software (2016); the proportions were compared using the Chi-square test or the Fisher test at the significance level of 5%. Results: Of 447 patients with diabetes mellitus, 49 had HCV positive serology and the sex ratio was 0.63. Seroprevalence of AC anti HCV was 11% (49/447); HCV RNA was detectable in 71.4% (n = 35) patients. The average age of the population was 62 ± 10 years with extremes ranging from 26 to 82 years. The circulating genotypes were 4 (97.1%) and 1 (2.8%). Subtyping was defined in 17.64% (n = 6) of genotype 4 patients; undefined in 82.36% (n = 28) of Genotype 4 patients, and in one of genotype 1 patients. The subtypes identified were subtype 4e (60%), subtype 4e (8.8%), subtype 4a/4c/4d (5.8%), and subtype 4h (2.9%).

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Virus de l’hépatite C : étude des génotypes au Congo (Brazzaville)

Cited by 3 publications

References 7 publications

Epidemiology of viral hepatitis in the Republic of Congo: review

Epidemiology of viral hepatitis in the Republic of Congo: review

Prevalence of Virological Markers HIV, HBV and HCV in Homozygous Sickle Cell Patients at Brazzaville University Hospital

Seroprevalence and Molecular Biodiverisity of Hepatitis C Infection in Congolese Diabetics

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