Virus induced apoptosis in PC12 rat phaeochromocytoma cells

Fábián, Zs.; Törőcsik, Beáta; Kiss, Katalin; Tigyi, J; Freeman, Ally N.; Csatary, Laszlo K.; Csatary, Christine M.; Liszka, V; Szeberényi, József

doi:10.1042/bst028a374a

Cited by 1 publication

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“…Currently, some studies seek to use vaccines against PCh and PGL. For example, the attenuated Newcastle Disease Virus vaccine showed a cytotoxic effect on the PC12 rat pheochromocytoma cell line in two independent studies [88,89]. Another study focused on chromogranin A-based vaccine.…”

Section: Cancer Vaccinesmentioning

confidence: 99%

Management of Pheochromocytomas and Paragangliomas: A Case-Based Review of Clinical Aspects and Perspectives

Sobocki

Perdyan

Szot

et al. 2022

JCM

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Paraganglioma and pheochromocytoma are rare medical conditions. Thus, there are still a small number of studies, clinical trials, and evidence-based data in this field. This makes clinical decisions more difficult. In this study, we present a case report enriched with a short review of available essential clinical data, indicating the need for constant metoxycatecholamine level observation and a proper diagnostic imaging approach, especially in terms of ongoing pandemics. Our research also provides a summary of the molecular background of these diseases, indicating their future role in clinical management. We analyzed the ClinicalTrials.gov dataset in order to show future perspectives. In this paper, the use of the PET-CT before MRI or CT is proposed in specific cases during diagnosis processes contrary to the guidelines. PET-CT may be as effective as standard procedures and may provide a faster diagnosis, which is important in periods with more difficult access to health care, such as during the COVID-19 pandemic.

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Section: Cancer Vaccinesmentioning

confidence: 99%