Virus-Induced Wheezing With COVID-19

Croup as a manifestation of COVID-19 in infancy: a case series

“…9 Nebulized epinephrine was the other intervention used in the admitted patients, keeping in mind the aerosol generating nature of the process, the amplified risk of transmission of infection to bystanders as well as need for appropriate personal protective equipment. 2 Inhaled corticosteroid in the form of budesonide which has been used in treating croup cases refractory to conventional therapy was not used in all of our patients. 8 Recent trials have also suggested the role of inhaled budesonide in reducing the likelihood of worsening disease as well as the length of hospital stay in adults with SARS-CoV-2 infection making it a plausible therapeutic choice in children with croup associated with COVID-19.…”

“…1 As the pandemic has evolved newer clinical presentations have come to the fore including with the rare occurrence of virus induced wheezing also being reported. 2 Similarly, the picture of upper airway obstruction as seen in croup manifesting with stridor amongst other classical features have only seldom been reported as a part of the SARS-CoV-2 clinical spectrum in children, with no such reports from India. 3,4 We hereby reported a series of three infants with SARS-C0V-2 infection who were brought to us in a span of one month (between 15 March and 15 April 2021) with the typical manifestations of acute laryngotracheitis with the presence of an audible stridor, all of whom responded to treatment with oxygen, nebulized epinephrine and steroids.…”