Visceral adipose tissue and body fat mass: Predictive values for and role of gender in cardiometabolic risk among Turks

Onat, Altan; Uğur, Murat; Can, Günay; Yüksel, Hüsniye; Hergenç, Gülay

doi:10.1016/j.nut.2009.05.019

Cited by 35 publications

(34 citation statements)

References 26 publications

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“…A similar gender difference regarding VAT has been described previously in a study on cardiometabolic risk; VAT was observed to be of greater relevance in men, whereas total FM was of most importance in women [37]. In addition, VAT was observed to be associated with insulin resistance and inflammatory markers primarily in men [38,39].…”

Section: Discussionsupporting

confidence: 69%

Adiposity and hand osteoarthritis: the Netherlands Epidemiology of Obesity study

et al. 2014

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IntroductionObesity, usually characterized by the body mass index (BMI), is a risk factor for hand osteoarthritis (OA). We investigated whether adipose tissue and abdominal fat distribution are associated with hand OA.MethodsThe Netherlands Epidemiology of Obesity (NEO) study is a population-based cohort aged 45 to 65 years, including 5315 participants (53% women, median BMI 29.9 kg/m2). Fat percentage and fat mass (FM) (kg) were estimated using bioelectrical impedance analysis. The waist-to-hip ratio (WHR) was calculated. In 1721 participants, visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) (cm2) were assessed using abdominal MR imaging. Hand OA was defined according to the ACR criteria.Odds ratios (OR) with 95% confidence intervals (CI) were calculated for the association of fat percentage, FM, WHR, VAT and SAT with hand OA using logistic regression analyses per standard deviation, stratified by sex and adjusted for age.ResultsHand OA was present in 8% of men and 20% of women. Fat percentage was associated with hand OA in men (OR 1.34 (95% CI 1.11 to 1.61)) and women (OR 1.26 (1.05 to 1.51)), as was FM. WHR was associated with hand OA in men (OR 1.45 (1.13 to 1.85)), and to a lesser extent in women (OR 1.17 (1.00 to 1.36)). Subgroup analysis revealed that VAT was associated with hand OA in men (OR1.33 (1.01 to 1.75)). This association increased after additional adjustment for FM (OR 1.51 (1.13 to 2.03)).ConclusionsFat percentage, FM and WHR were associated with hand OA. VAT was associated with hand OA in men, suggesting involvement of visceral fat in hand OA.

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Section: Discussionsupporting

confidence: 69%

Adiposity and hand osteoarthritis: the Netherlands Epidemiology of Obesity study

et al. 2014

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“…However, deposition of fat into ectopic areas depends on total body FM and an individual’s basic susceptibility that, in turn, is related to age, sex, and ethnicity. Onat et al 17 showed that visceral adiposity in men measured with a similar bioelectrical impedance analyzer (Tanita TBF 300, Tokyo, Japan) seems to be of greater relevance in cardiometabolic risk of Turkish adults. In the current study, higher specificity values with a higher threshold in men were achieved, which adds new insights to this conclusion.…”

Section: Discussionmentioning

confidence: 99%

Performance of Bioelectrical Impedance Analysis in the Diagnosis of Metabolic Syndrome

Özhan

Alemdar

Caglar

et al. 2012

Journal of Investigative Medicine

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“…In particular, women have higher concentrations of inflammatory markers, such as high sensitivity C reactive protein (hs-CRP), compared to men, attributed possibly to their increased accumulation of subcutaneous and/or visceral fat [60,61]. Additionally, factors others than those included in the existing definitions of MetS, such as endothelial dysfunction, small dense oxidized LDL, insulin resistance, prothrombotic tendency and a proinflammatory state that are essential components and determinant of future cardiometabolic risk have been left out.…”

Section: Introductionmentioning

confidence: 99%

Metabolic syndrome: definitions and controversies

Kassi

Pervanidou

Kaltsas

et al. 2011

BMC Med

1,216

855

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Metabolic syndrome (MetS) is a complex disorder defined by a cluster of interconnected factors that increase the risk of cardiovascular atherosclerotic diseases and diabetes mellitus type 2. Currently, several different definitions of MetS exist, causing substantial confusion as to whether they identify the same individuals or represent a surrogate of risk factors. Recently, a number of other factors besides those traditionally used to define MetS that are also linked to the syndrome have been identified. In this review, we critically consider existing definitions and evolving information, and conclude that there is still a need to develop uniform criteria to define MetS, so as to enable comparisons between different studies and to better identify patients at risk. As the application of the MetS model has not been fully validated in children and adolescents as yet, and because of its alarmingly increasing prevalence in this population, we suggest that diagnosis, prevention and treatment in this age group should better focus on established risk factors rather than the diagnosis of MetS.

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Visceral adipose tissue and body fat mass: Predictive values for and role of gender in cardiometabolic risk among Turks

Cited by 35 publications

References 26 publications

Adiposity and hand osteoarthritis: the Netherlands Epidemiology of Obesity study

Adiposity and hand osteoarthritis: the Netherlands Epidemiology of Obesity study

Performance of Bioelectrical Impedance Analysis in the Diagnosis of Metabolic Syndrome

Metabolic syndrome: definitions and controversies

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