Visceral Adiposity Index in Breast Cancer Survivors: A Case-Control Study

Abstract

Background. Breast cancer (BC) is the first cause of cancer morbidity and mortality in women. This disease has been linked to obesity; however, it is not clear how fat accumulation affects women who survive breast cancer. Although the visceral adiposity index (VAI) is a marker of cardiometabolic risk and adipose tissue dysfunction, it is not clear how it changes in breast cancer survivors. The aim of this investigation was to compare VAI in women with and without breast cancer. Methods. A case-control cross-sectional study was conducted on women who were BC survivors and women without the history of BC (control group). Body composition was assessed using electrical bioimpedance while VAI by means of waist circumference (WC), body mass index (BMI), triacylglycerols (TG), and high-density lipoprotein cholesterol (HDL-C). Results. 49 women in the BC survivor group and 50 in the control group. WC was wider in the survivor group as regards control (93.65 ± 10.48 vs. 88.52 ± 9.61 cm) ( p = 0.025 ); at once, TG and VAI were significantly higher for the survivor group (243.55 ± 199.84 vs. 159.84 ± 75.77) ( p = 0.007 ) and (11.03 ± 11.15 vs. 6.41 ± 3.66) ( p < 0.005 ), respectively. Body composition parameters were similar in both groups. Conclusions. VAI is higher in women who are BC survivors in comparison with controls matched by age and bodyweight.

An Evaluation of Metabolic, Dietetic, and Nutritional Status Reveals Impaired Nutritional Outcomes in Breast Cancer Patients

“…Moreover, Godinho-Mota et al (2020) reported a visceral fat dysfunction among breast cancer patients after chemotherapy 15 . Considering visceral fat accumulation, the adiposity indices as the visceral adiposity index (VAI), lipid accumulation product index (LAP), and triglyceride glucose index (TyG), could be important metabolic alterations tracking tools [16][17][18][19][20] . Furthermore, in a previous study, our research group found a metabolic syndrome prevalence of more than 50% of breast cancer survivors 21 , and the combination of those alterations with unhealthy body composition and improperly food intake might lead to the development of secondary illness, for instance, the cardiovascular diseases in breast cancer survivors [22][23][24] , reflecting directly to the survival rates and clinical evolution after the cancer care.…”

An evaluation of metabolic, dietetic, and nutritional status reveals impaired nutritional outcomes in breast cancer patients undergoing chemotherapy compared with a matched control group

“…Moreover, Godinho-Mota et al (2020) reported a visceral fat dysfunction among breast cancer patients after chemotherapy 15 . Considering visceral fat accumulation, the adiposity indices as the visceral adiposity index (VAI), lipid accumulation product index (LAP), and triglyceride glucose index (TyG), could be important metabolic alterations tracking tools [16][17][18][19][20] . Furthermore, in a previous study, our research group found a metabolic syndrome prevalence of more than 50% of breast cancer survivors 21 , and the combination of those alterations with unhealthy body composition and improperly food intake might lead to the development of secondary illness, for instance, the cardiovascular diseases in breast cancer survivors [22][23][24] , reflecting directly to the survival rates and clinical evolution after the cancer care.…”