Visceral fat accumulation as a predictor of coronary artery calcium as assessed by multislice computed tomography in Japanese patients

Ohashi, Norihiko; Yamamoto, Hideya; Horiguchi, Jun; Kitagawa, Toshiro; Hirai, Nobuhiko; Ito, Katsuhide; Kohno, Nobuoki

doi:10.1016/j.atherosclerosis.2008.04.019

Cited by 62 publications

(44 citation statements)

References 30 publications

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“…The VFA is considered to play an important role in the onset of metabolic syndrome and atherosclerosis (35,36), which is affected by age, gender and the level of obesity (37,38). CRP is an inflammatory biomarker and strong independent predictor of diabetes (39) reported to be strongly correlated with metabolic risk factors (40).…”

Section: Discussionmentioning

confidence: 99%

Association between the Postprandial Glucose Levels and Arterial Stiffness Measured According to the Cardio-ankle Vascular Index in Non-diabetic Subjects

Tsuboi

Ito²,

Fujikawa³

et al. 2015

Intern. Med.

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Objective Although a relationship between post-challenge hyperglycemia and arterial stiffness has been reported, the relationship between the postprandial glucose levels and cardio-ankle vascular index (CAVI) in non-diabetic subjects is not clear. This study thus evaluated the association between the postprandial glucose levels after a composite meal and the degree of arterial stiffness measured according to CAVI in non-diabetic subjects. Methods The subjects included 1,291 individuals (655 men and 636 women; mean age, 48.6 years; range, 23-85 years) who underwent medical examinations, including blood tests and CAVI assessments, between October 2005 and April 2012. The 1-hour postprandial glucose levels were determined after a 600-kcal traditional Japanese meal. ResultsThe CAVI values were significantly higher in the subjects with higher 1-hour postprandial glucose levels (! 140 mg/dL in men; ! 158 mg/dL in women). A simple regression analysis indicated that the CAVI values were significantly correlated with the 1-hour postprandial glucose levels in men (r=0.286, p<0.0001) and women (r=0.228, p<0.0001). After adjusting for age, BMI, systolic blood pressure, triglycerides, highdensity lipoprotein cholesterol, low-density lipoprotein cholesterol, 1-hour postprandial glucose, homeostatis model assessment of insulin resistance, estimated glemerular filtration rate, and high sensitive C-reactive protein, stepwise multiple regression analysis demonstrated that the 1-hour postprandial glucose level was an independent predictor associated with the CAVI in men (p=0.003) and older women 50 years of age or older (p=0.003). Conclusion This study demonstrated that the 1-hour postprandial glucose levels are associated with increased CAVI values in non-diabetic men and older women 50 years of age or older.

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Section: Discussionmentioning

confidence: 99%

Association between the Postprandial Glucose Levels and Arterial Stiffness Measured According to the Cardio-ankle Vascular Index in Non-diabetic Subjects

Tsuboi

Ito²,

Fujikawa³

et al. 2015

Intern. Med.

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“…We calculated CAC scores using dedicated software (Smartscore, version 3.5; GE Healthcare). 18 During an inspiratory breath hold, contrastenhanced scanning was performed by a retrospective ECGgated scan using the helical mode or prospective ECG-triggered CTA (with the center of the imaging window corresponding to 75% of the R-R interval) based on our previous report. 19, 20 A body weight-adjusted volume (0.6 ml/kg) of iodine-based contrast medium was injected into the antecubital vein over the course of 10s, followed by a 25-ml 0.9% NaCl solution flush over 5s.…”

Section: Ectopic Adiposity and Coronary Atherosclerosismentioning

confidence: 99%

Association of Epicardial and Abdominal Visceral Adipose Tissue With Coronary Atherosclerosis in Patients With a Coronary Artery Calcium Score of Zero

Tsushima

Yamamoto

Kitagawa

et al. 2015

Circ J

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“…VFA in each subject was automatically determined by an image at the level of the umbilicus using dedicated software on abdominal CT as described previously 16 .…”

Section: Measurement Of Visceral Fat Areamentioning

confidence: 99%

The impact of abdominal aortic calcification and visceral fat obesity on lower urinary tract symptoms in patients with benign prostatic hyperplasia

Motoya

Matsumoto

Yamaguchi³

et al. 2014

Int Urol Nephrol

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Visceral fat accumulation as a predictor of coronary artery calcium as assessed by multislice computed tomography in Japanese patients

Cited by 62 publications

References 30 publications

Association between the Postprandial Glucose Levels and Arterial Stiffness Measured According to the Cardio-ankle Vascular Index in Non-diabetic Subjects

Association between the Postprandial Glucose Levels and Arterial Stiffness Measured According to the Cardio-ankle Vascular Index in Non-diabetic Subjects

Association of Epicardial and Abdominal Visceral Adipose Tissue With Coronary Atherosclerosis in Patients With a Coronary Artery Calcium Score of Zero

The impact of abdominal aortic calcification and visceral fat obesity on lower urinary tract symptoms in patients with benign prostatic hyperplasia

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