Visceral Larva Migrans-Like Syndrome Caused by Angiostrongylus Costaricensis *

Morera, Pedro; Pérez, Francisco F. García; Mora, Fernando; Castro, Luis Antônio Suíta de

doi:10.4269/ajtmh.1982.31.67

Cited by 27 publications

(18 citation statements)

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“…According to this author, in the rodent the cycle takes place entirely in the abdominal cavity, and the young adults migrate to their definitive habitat by moving from the lymphatic vessels to the mesenteric arteries through the vascular walls provoking multiple small hemorrhages around the vessels. However, several reports on naturally infected animals and patients have described the occurrence of different parasitic stages (eggs, L1, and adult worms) in other organs not mentioned in the original description of the life history of A. costaricensis (Velazquez et al 1974, Morera et al 1982, Duarte et al 1991, Vazquez et al 1994, Brack & Schropel 1995, Zuccaro et al 1998. In order to elucidate these findings on migratory pathways of A. costaricensis, Mota and Lenzi (1995) have proposed a new conception of this nematode life cycle based on a mouse model similar to the other Metastrongylides.…”

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confidence: 99%

Angiostrongylus costaricensis: complete redescription of the migratory pathways based on experimental Sigmodon hispidus infection

Mota

Lenzi

2005

Mem. Inst. Oswaldo Cruz

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confidence: 99%

Angiostrongylus costaricensis: complete redescription of the migratory pathways based on experimental Sigmodon hispidus infection

Mota

Lenzi

2005

Mem. Inst. Oswaldo Cruz

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“…The final events of this injury may vary between intestinal infarct, intestinal perforation, formation of pseudotumor or acute appendicitis 2,3 . Otherwise, liver involvement is unusual, with publications restricted to case reports 7,11,16 . The finding of tender hepatomegaly combined with slight increase in aminotranspherases and marked eosinophilia should raise suspicion for AA.…”

Section: Discussionmentioning

confidence: 99%

“…The finding of tender hepatomegaly combined with slight increase in aminotranspherases and marked eosinophilia should raise suspicion for AA. MORERA et al 11 considered the A. costaricensis adult worm migration to intrahepatic portal veins as a visceral larva-migrans-like syndrome. However, MOTA & LENZI 12,13 , using two different animal models (Swiss Webster and Sigmodon hispidus) showed that the A. costaricensis presents, during its life cycle, an alternative migration to hepatic veins as a normal event of venous portal pathway, where the nematode matures and lays fertile eggs inside the liver.…”

Section: Discussionmentioning

confidence: 99%

Abdominal angiostrongyliasis: report of two cases with different clinical presentations

Rodriguez

Dequi

Peruzzo

et al. 2008

Rev. Inst. Med. trop. S. Paulo

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SUMMARYAbdominal angiostrongyliasis is a sporadic infectious disease caused by the nematode Angiostrongylus costaricensis. It usually presents as acute abdomen, secondary to mesenteric ischemia, and pronounced eosinophilia. In some cases its course is insidious and transient, and the diagnosis is suspicious. The disease is confirmed by the detection of A. costaricensis elements in surgical specimen. The treatment is supportive, with avoidance of antihelminthic administration due to a possible erratic migration followed by worsening of the disease. We report two cases, both with intense eosinophilia and serum IgG-ELISA positive to A. costaricensis. The first case presented ileal perforation and was surgically treated. The second one showed hepatic nodules at ultrasound and was only symptomatically treated, evolving to an apparent protracted resolution. These two cases exemplify different clinical forms of the disease, one of them with liver involvement.

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“…Complications such as occlusive syndrome, peritonitis due to intestinal perforation, ulcers and hemorrhage, may occur. Ectopic localizations in the liver 16 and in the spermatic cord in small boys 21 have been also described. Man is an accidental host for this zoonotic infection.…”

Section: Morera and Céspedes (1971) Describedmentioning

confidence: 99%

Human infection by Angiostrongylus costaricensis in Venezuela: first report of a confirmed case

Incani

Caleiras²,

Rodríguez‐Martín³

et al. 2007

Rev. Inst. Med. trop. S. Paulo

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SUMMARYA proven case of human infection caused by Angiostrongylus costaricensis is reported for the first time in Venezuela. The patient was a 57-year-old female surgically operated because of signs of peritonitis with a palpable mass at the lower right quadrant of the abdomen. WBC count reported 16,600 cells/mm 3 , with 46% eosinophils. The tumoral aspect of ileocolic area and peritoneal lymph nodes prompted the resection of a large area of the terminal ileum, cecum, part of the ascending colon and a small part of the jejunum, where a small lesion was found. The pathology showed thickened areas of the intestinal wall with areas of hemorrhage and a perforation of the cecum. Histology showed intense eosinophil infiltration of the whole intestinal wall, granulomas with giant cells and eosinophils. Some of the granuloma surrounded round or oval eggs with content characterized by a large empty area, cells or embryo in the center, and sometimes nematode larvae. A cross section of an adult nematode worm was observed inside a branch of mesenteric artery. The intestinal affected area, the characteristics of the lesions, the presence of eggs in the submucosa with nematode larvae inside, and the observation of a nematode inside a mesenteric artery, makes sufficient criteria for the diagnosis of an infection by Angiostrongylus costaricensis.

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Visceral Larva Migrans-Like Syndrome Caused by Angiostrongylus Costaricensis *

Cited by 27 publications

References 0 publications

Angiostrongylus costaricensis: complete redescription of the migratory pathways based on experimental Sigmodon hispidus infection

Angiostrongylus costaricensis: complete redescription of the migratory pathways based on experimental Sigmodon hispidus infection

Abdominal angiostrongyliasis: report of two cases with different clinical presentations

Human infection by Angiostrongylus costaricensis in Venezuela: first report of a confirmed case

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