Viscoelastic adherence to corneal endothelium following phacoemulsification

Abstract

Median thickness of Amvisc Plus, Healon GV, and Viscoat remaining adherent to the corneal endothelium after phacoemulsification was markedly different. Viscoat provided the greatest amount of viscoelastic material adjacent to the corneal endothelium.

Quantitative thermographic analysis of viscoelastic substances in an experimental study in rabbits

“…This difference in MT may depend on rheologic properties of the OVDs such as adhesion, retention, and temperature transmission. The findings in this study are supported by the finding of McDermott et al 12 that the amount of adherent OVD is highly dependent on its type and by the finding of Glasser et al 13 regarding the greater intraocular retentive tendency of Viscoat than of cohesive OVDs such as Provisc. Moreover, Viscoat has 3 negative charges per molecular unit that provide a greater neutralizing effect on positively charged ocular tissue, which better explains the coatability of the corneal endothelium.…”

Free Radicals in Phacoemulsification and Aspiration Procedures

“…Viscoat coats the endothelial cells to a thicker degree than any other agents after a PEA procedure. 19 In this study, the longest US duration was 30 seconds in the eye model experiment, while it is usually longer than 30 seconds during clinical PEA. Presumably, the longer US time would cause the more enhanced signals.…”

“…Yet, it is likely that Viscoat would remain in the anterior chamber to some extent even after a longer duration and consequently inhibit the signals, considering the results of the previously cited reports. [17][18][19] The evidence so far is that the more dispersive the agent is, the more retention that is seen in the anterior chamber during and after PEA. The present results suggest that the anti-free radical effect of the OVD depends on its retention in the anterior chamber during PEA.…”

Visco-shell technique with sodium hyaluronate 2.3% in phacoemulsification of Morgagnian cataract

“…We suggest that the appropriate use of OVDs is highly effective in preventing such intraoperative complications. Several facts are known about the properties of OVDs: Dispersive OVDs are retained in the eye better than cohesive OVDs [11][12][13][14] ; with an I/A tip, the removal time is longer with dispersive OVDs and shorter with cohesive OVDs [12][13][14] ; and the removal of viscoadaptive OVDs is faster than the removal of dispersive OVDs but slower than the removal of cohesive OVDs. 4,5,10,13,14 A viscoadaptive OVD is designed to change its behavior at flow rates of approximately 25 cc/min.…”