Viscoelastic Testing Methods

Carll, Timothy

doi:10.1016/bs.acc.2023.09.001

Cited by 3 publications

(2 citation statements)

References 125 publications

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“…From this curve, information is provided on clot time, clot stiffness, platelet contribution to clot stiffness, fibrinogen contribution to clot stiffness and clot stability to fibrinolysis. The output parameters are comparable to those reported by thromboelastography and thromboelastometry [9]. Several studies have shown a high level of correlation between SEER sonorheometry parameters and equivalent parameters reported by thromboelastometry and thromboelastography [7,10].…”

Section: Discussionsupporting

confidence: 81%

A resonance sonorheometry guided dose reduction of plasma transfusion in repetitive hip surgery in a patient with a severe factor XI deficiency: a case report

Supthut,

Peck,

Hertenstein

et al. 2024

Anaesthesia Reports

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SummaryFactor XI deficiency is a rare disorder with an unpredictable bleeding tendency. Here, we report the successful use of the sonic estimation of elasticity via resonance sonorheometry for guiding the management of haemostasis in a patient with a severe factor XI deficiency in repeated revision hip surgeries. Regardless of an administration of fresh frozen plasma, a significant haemorrhage occurred at the first of three hip surgeries. The repeat application of fresh frozen plasma normalised the prolonged activated partial thromboplastin time and the resonance sonorheometry clot time values; the factor XI activity increased to a sufficient level. No significant bleeding occurred in the second and third hip surgery. Using a resonance sonorheometry guided approach in haemostasis management has the potential to improve safety for patients with factor XI deficiency undergoing surgery by ensuring sufficient clotting and preventing side effects.

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Section: Discussionsupporting

confidence: 81%

A resonance sonorheometry guided dose reduction of plasma transfusion in repetitive hip surgery in a patient with a severe factor XI deficiency: a case report

Supthut,

Peck,

Hertenstein

et al. 2024

Anaesthesia Reports

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“…Viscoelastic testing (VET) represents a real-time whole blood assessment of ex-vivo coagulation, reflecting the interaction between plasma, platelets and other blood cells involved in hemostasis [ 1 ]. VET includes both Thromboelastography (TEG ® ), Rotational Thromboelastography (ROTEM ® ) and several other more recent testing platforms [ 2 , 3 , 4 , 5 , 6 ]. The basic principle of classical VET involves electromagnetic or other sensors that allow detection of the torque of a pin which sits in a cup of liquid, initially with non-clotted blood, with varying methods which differ according to the manufacturer; notably, in TEG ® or ClotPro ® compared with ROTEM ® , whether the pin or the cup oscillates with time.…”

Section: Introduction and Principles Of Viscoelastic Testingmentioning

confidence: 99%

The Role of Viscoelastic Testing in Assessing Hemostasis: A Challenge to Standard Laboratory Assays?

Reardon,

Pasalic,

Favaloro

2024

JCM

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Viscoelastic testing is increasingly being used in clinical and research settings to assess hemostasis. Indeed, there are potential situations in which viscoelastic testing is reportedly superior to standard routine laboratory testing for hemostasis. We report the current testing platforms and terminology, as well as providing a concise narrative review of the published evidence to guide its use in various clinical settings. Notably, there is increasing evidence of the potential utility of viscoelastic testing for assessment of direct oral anticoagulants, and bleeding associated with chronic liver disease, orthotopic liver transplantation, cardiac surgery, trauma, obstetrics and pediatrics.

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Hemostasis in Pre-Eclamptic Women and Their Offspring: Current Knowledge and Hemostasis Assessment with Viscoelastic Tests

Kontovazainitis,

Gialamprinou,

Theodoridis

et al. 2024

Diagnostics

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Pre-eclampsia (PE) is a placenta-mediated disease and remains a major cause of maternal and neonatal mortality and morbidity. As PE develops, normal pregnancy’s hypercoagulable balance is disrupted, leading to platelet hyperactivation, excessive pathological hypercoagulability, and perturbed fibrinolysis. This narrative review aims to summarize the current knowledge regarding hemostasis in PE compared with healthy gestation and the potential effects of maternal PE on neonatal hemostasis. Finally, it aims to discuss hemostasis assessments for normal pregnancies and PE, emphasizing the role of viscoelastic tests, namely, thromboelastography (TEG) and thromboelastometry (ROTEM), for monitoring PE-associated hemostatic alterations. The use of TEG/ROTEM for assessing the hemostatic profile of PE women has been little considered, even though conventional coagulation tests (CCTs) have not helped to monitor hemostasis in this population. Compared with normal pregnancy, TEG/ROTEM in PE reveals an excessive hypercoagulability analogous with the severity of the disease, characterized by higher-stability fibrin clots. The TEG/ROTEM parameters can reflect PE severity and may be used for monitoring and as predictive markers for the disease.

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Viscoelastic Testing Methods

Cited by 3 publications

References 125 publications

A resonance sonorheometry guided dose reduction of plasma transfusion in repetitive hip surgery in a patient with a severe factor XI deficiency: a case report

A resonance sonorheometry guided dose reduction of plasma transfusion in repetitive hip surgery in a patient with a severe factor XI deficiency: a case report

The Role of Viscoelastic Testing in Assessing Hemostasis: A Challenge to Standard Laboratory Assays?

Hemostasis in Pre-Eclamptic Women and Their Offspring: Current Knowledge and Hemostasis Assessment with Viscoelastic Tests

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