Visible light-driven organic photochemical synthesis in China

Visible‐Light‐Promoted Selenylative Spirocyclization of Indolyl‐ynones toward the Formation of 3‐Selenospiroindolenine Anticancer Agents

“…[10] In particular, visible-light photoredox catalysis using O 2 as the oxidant is regarded as an ideal methodology for the oxidative functionalization reactions owing to its economical, safe and environmentally friendly properties. [11] In 2018, Baidya's group reported a radical dearomative cascade cyclization to selenylative spirocyclization of N-aryl alkynamides at room temperature under oxygen atmosphere (Scheme 1a). [12] Unsworth's group reported a visible-light-induced intramolecular charge transfer in the radical spirocyclisation of indol ynones with thiols leading the formation of 3-thiospiroindolenines under the argon condition, in which an intramolecular EDA complex was formed (Scheme 1b).…”

“…The single crystals of 3 a was obtained by gradual crystallization in methanol, and character- [16] Then, the investigation of various bases such as Na 2 CO 3 , NaHCO 3 , K 2 CO 3 , Cs 2 CO 3 , NaOAc and KOAc revealed that NaOAc was the optimal base for this reaction and afforded 3 a in 80% yield (Table 1, entries 6 vs 2-7). In addition, a solvent screening study indicated that THF was the most suitable solvent for the formation of 3 a (Table 1, entries 6 vs [8][9][10][11][12]. Moreover, when the reaction was conducted in sunshine, the product 3 a was obtained in 86% yield (Table 1, entry 13).…”

Selective photocatalytic oxidation of aromatic alcohols to aldehydes with air by magnetic WO3ZnO/Fe3O4. In situ photochemical synthesis of 2-substituted benzimidazoles

“…The visible region of the solar energy ($43%) is the most useful alternative to perform many green organic photochemical reactions under catalytic conditions due to its sustainable and abundant nature. 1 Therefore, a great deal of concern is devoted to the photocatalytic degradation of organic wastes in water resources, efficient photocatalytic oxyfunctionalization of organic compounds and selective organic transformations under ambient environmentally friendly conditions, in particular with atmospheric air as a natural oxidant, under solar light. [2][3][4][5][6] Among various organic transformations, the selective photochemical oxidation of alcohols to carbonyl compounds is of prime importance due to its signicant role in the synthesis of a variety of ne chemicals, confectionaries, fragrances, and pharmaceutical industries.…”

Recent Advances in Enantioselective Photochemical Reactions of Stabilized Diazo Compounds

“…One of the major goals for the advancement of modern organic synthesis is the development of green and efficient methods that allow the rapid construction of chiral molecules from readily available starting materials [17]. In this endeavor, photocatalysis represents a unique and green strategy that has contributed much to the developments towards the synthesis of optically enriched compounds [18,19,20,21,22,23,24] and has also renewed interest in the asymmetric photochemistry of diazo compounds. The past two decades have been the most productive period of this chemistry, which is achieved by a better understanding of the reactivity of diazo compounds and the emergence of new catalytic modes.…”